Details of Disease | DrugMAP

General Information of Disease (ID: DIS93JJO)

Disease Name	Nerve compression syndrome
Synonyms	peripheral nerve entrapment syndrome; entrapment neuropathy; compression neuropathy
Definition	Any nerve disorder caused by the entrapment and compression of a nerve.
Disease Hierarchy	DIS7KN5G: Peripheral neuropathy DIS93JJO: Nerve compression syndrome
Disease Identifiers	MONDO ID MONDO_0003615 MESH ID D009408 UMLS CUI C1510429 MedGen ID 266933 HPO ID HP:0012181 SNOMED CT ID 45781009

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
MAG	TT9XFON	moderate	Biomarker	[1]
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This Disease Is Related to 1 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
UCK1	DE478BP	moderate	Biomarker	[2]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
REEP1	OTEMVFX7	Strong	Genetic Variation	[3]
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References

1	Local down-regulation of myelin-associated glycoprotein permits axonal sprouting with chronic nerve compression injury.Exp Neurol. 2006 Aug;200(2):418-29. doi: 10.1016/j.expneurol.2006.02.134. Epub 2006 Jun 9.
2	Up-regulated uridine kinase gene identified by RLCS in the ventral horn after crush injury to rat sciatic nerves.Biochem Biophys Res Commun. 1999 Dec 9;266(1):104-9. doi: 10.1006/bbrc.1999.1781.
3	Peripheral neuropathy in hereditary spastic paraplegia caused by REEP1 variants.J Neurol. 2019 Mar;266(3):735-744. doi: 10.1007/s00415-019-09196-1. Epub 2019 Jan 12.