Details of Disease | DrugMAP

General Information of Disease (ID: DISBYU1Y)

Disease Name	Noonan syndrome 13
Synonyms	NS13
Disease Hierarchy	DIS7Q7DN: Noonan syndrome DISBYU1Y: Noonan syndrome 13
Disease Identifiers	MONDO ID MONDO_0033669 UMLS CUI C5436773 OMIM ID 619087 MedGen ID 1761918

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
MAPK1	TT4TQBX	Strong	Autosomal dominant	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
MAPK1	OTH85PI5	Strong	Autosomal dominant	[1]
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References

1	MAPK1E322K mutation increases head and neck squamous cell carcinoma sensitivity to erlotinib through enhanced secretion of amphiregulin. Oncotarget. 2016 Apr 26;7(17):23300-11. doi: 10.18632/oncotarget.8188.