Details of Disease | DrugMAP

General Information of Disease (ID: DISDA2EP)

Disease Name	Vesicoureteral reflux 8
Synonyms	VUR8; TNXB vesicoureteral reflux (disease); vesicoureteral reflux 8; vesicoureteral reflux (disease) caused by mutation in TNXB; vesicoureteral reflux type 8
Definition	Any vesicoureteral reflux in which the cause of the disease is a mutation in the TNXB gene.
Disease Hierarchy	DISUME5E: Familial vesicoureteral reflux DISDA2EP: Vesicoureteral reflux 8
Disease Identifiers	MONDO ID MONDO_0014422 UMLS CUI C4014831 OMIM ID 615963 MedGen ID 863268

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
TNXB	OTVBWAV5	Limited	Autosomal dominant	[1]
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References

1	Increased sensitivity for detection of carcinogen-induced DNA repair with the chain terminator dideoxythymidine. Biochem Biophys Res Commun. 1978 Aug 29;83(4):1538-44. doi: 10.1016/0006-291x(78)91396-7.