Details of Disease

General Information of Disease (ID: DISDOC9I)

• Disease Name: Loiasis
• Synonyms: African eye worm; Loa loa filariasis
• Definition: Loiasis is a form of filariasis (see this term), caused by the parasitic worm Loa loa, endemic to the forest and savannah regions of Central and Western Africa. Loiasis may either be asymptomatic or manifest as a large, transient area of localized, non-erythematous subcutaneous edema (Calabar swellings), adult worm migration through the sub-conjunctiva (''African eye worm'') and pruritus. Generalized itching, hives, muscle pains, arthralgias, fatigue, and adult worms visibly migrating under the surface of the skin may be observed. Severe complications such as encephalopathy have been reported in highly infected individuals receiving ivermectin during mass drug administration programs for the control of onchocerciasis and lymphatic filariasis.
• Disease Hierarchy:
  DISWBRRN: Filarial disease
  DISDOC9I: Loiasis
• Disease Identifiers:
  MONDO ID: MONDO_0016566
  MESH ID: D008118
  UMLS CUI: C0023968
  MedGen ID: 6132
  Orphanet ID: 2404
  SNOMED CT ID: 44250009

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Diethylcarbamazine	DM1TJ8F	Approved	Small molecular drug	[1]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Diethylcarbamazine FDA Label