Details of Disease

General Information of Disease (ID: DISH6EOW)

• Disease Name: Gonococcal urethritis
• Synonyms: Gonococcal urethritis; gonococcal urethritis; gc urethritis
• Disease Class: 1A70-1A7Z: Gonococcal infection
• Definition: Inflammation of the urethra secondary to infection with Neisseria gonorrhoeae; this infection is spread through sexual contact.
• Disease Hierarchy:
  DISSWPSQ: Urethritis
  DISQ5AO6: Gonorrhea
  DISEM33Q: Infectious disease
  DISH6EOW: Gonococcal urethritis
• ICD Code:
  ICD-11: ICD-11: 1A70.0Y
  ICD-10: ICD-10: A54.1
  ICD-9: ICD-9: 98
  Expand ICD-11: '1A70.1
  Expand ICD-10: 'A54.1
  Expand ICD-9: 98
• Disease Identifiers:
  MONDO ID: MONDO_0020971
  UMLS CUI: C0018078
  MedGen ID: 42278
  SNOMED CT ID: 236682002

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Pefloxacin	DM49IGF	Approved	Small molecular drug	[1]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
GSS	TTVEWR4	Limited	Genetic Variation	[2]

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CUL9	OTPUCLZT	Limited	Genetic Variation	[3]

References

• [1] Drug information of Pefloxacin, 2008. eduDrugs.
• [2] Microscopy of Gram-stained urethral smear in the diagnosis of urethritis: Which threshold value should be selected?.Andrologia. 2018 Dec;50(10):e13143. doi: 10.1111/and.13143. Epub 2018 Sep 20.
• [3] Mutations in the gyrA and parC genes and in vitro activities of fluoroquinolones in 91 clinical isolates of Neisseria gonorrhoeae in Japan.Sex Transm Dis. 2004 Mar;31(3):180-4. doi: 10.1097/01.olq.0000114654.91972.66.