Details of Disease | DrugMAP

General Information of Disease (ID: DISHA0ML)

Disease Name	Legionellosis
Synonyms	Legionella infection; Legionnaires disease
Definition	Any disease caused by Legionella bacteria.
Disease Hierarchy	DIS8ZVFW: Primary bacterial infectious disease DISHA0ML: Legionellosis
Disease Identifiers	MONDO ID MONDO_0005823 MESH ID D007876 UMLS CUI C0023240 MedGen ID 7292 Orphanet ID 549 SNOMED CT ID 26726000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
PIKFYVE	TTA4M1N	Strong	Biomarker	[1]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
AWAT2	OTO5GKZS	Strong	Biomarker	[2]
SUMF2	OT37I8JL	Strong	Biomarker	[3]
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References

1	PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection.PLoS Pathog. 2019 Feb 7;15(2):e1007551. doi: 10.1371/journal.ppat.1007551. eCollection 2019 Feb.
2	Sequence-based typing of Legionella pneumophila strains isolated from hospital water distribution systems as a complementary element of risk assessment of legionellosis in Poland.Ann Agric Environ Med. 2013;20(3):436-40.
3	A legionellosis case due to contaminated spa water and confirmed by genomic identification in Taiwan.Microbiol Immunol. 2006;50(5):371-7. doi: 10.1111/j.1348-0421.2006.tb03803.x.