Details of Disease

General Information of Disease (ID: DISHKOLS)

• Disease Name: Autosomal dominant ichthyosis vulgaris
• Synonyms: ichthyosis vulgaris; ichthyosis simplex; dominant ichthyosis vulgaris; dominant congenital ichthyosiform erythroderma; autosomal dominant ichthyosis vulgaris; ichthyosis vulgaris, autosomal dominant
• Definition: Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin. It often begins in early childhood. Treatment may include heavy duty moisturizers which contain chemicals that help the skin to shed normally, including lactic acid, salicylic acid, and urea. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. The condition usually disappears during adulthood, but may return in later years. This condition is inherited in an autosomal dominant pattern.
• Disease Hierarchy:
  DISTRF9L: Ichthyosis vulgaris
  DIS3HIWD: Autosomal dominant disease
  DISHKOLS: Autosomal dominant ichthyosis vulgaris
• Disease Identifiers:
  MONDO ID: MONDO_0007810
  UMLS CUI: C0432300
  MedGen ID: 609440
  Orphanet ID: 462
  SNOMED CT ID: 254158000

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
FLG	OTE9QDV6	Definitive	Semidominant	[1]

References

• [1] The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.