Details of Disease | DrugMAP

General Information of Disease (ID: DISHLH3F)

Disease Name	Autosomal dominant nonsyndromic hearing loss 22
Synonyms	DFNA 22; autosomal dominant nonsyndromic deafness caused by mutation in MYO6; DFNA22; deafness, autosomal dominant 22; deafness, autosomal dominant nonsyndromic sensorineural 22; autosomal dominant nonsyndromic deafness 22; MYO6 autosomal dominant nonsyndromic deafness; autosomal dominant deafness 22; deafness, autosomal dominant 22, with hypertrophic cardiomyopathy; deafness, autosomal dominant type 22; autosomal dominant nonsyndromic deafness type 22
Definition	Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the MYO6 gene.
Disease Hierarchy	DISYC1G0: Autosomal dominant nonsyndromic hearing loss DISHLH3F: Autosomal dominant nonsyndromic hearing loss 22
Disease Identifiers	MONDO ID MONDO_0011660 MESH ID C538197 UMLS CUI C2931767 OMIM ID 606346 MedGen ID 419894

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
MYO6	OTJQYRC7	Strong	Autosomal dominant	[1]
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References

1	Novel myosin mutations for hereditary hearing loss revealed by targeted genomic capture and massively parallel sequencing. Eur J Hum Genet. 2014 Jun;22(6):768-75. doi: 10.1038/ejhg.2013.232. Epub 2013 Oct 9.