Details of Disease

General Information of Disease (ID: DISIBJSM)

Disease Name Posterior uveitis
Synonyms inflammation of chorioretinal region; chorioretinal region inflammation; uveitis, posterior
Definition
Inflammation of the choroid as well as the retina and vitreous body. Some form of visual disturbance is usually present. The most important characteristics of posterior uveitis are vitreous opacities, choroiditis, and chorioretinitis.|Editor note: choroid=PU. in MESH PUitis is defined to be choroid+retina+VB, and isa panuveitis. TODO check ORDO, GARD
Disease Hierarchy
DISV0RYS: Uveitis
DISWD40R: Disease
DISIBJSM: Posterior uveitis
Disease Identifiers
MONDO ID
MONDO_0006918
MESH ID
D015866
UMLS CUI
C0042167
MedGen ID
22597
HPO ID
HP:0012123
SNOMED CT ID
43363007

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CCL5 TT9DWLC Strong Biomarker [1]
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This Disease Is Related to 2 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
RBP3 OTIWM4GT Limited Biomarker [2]
HLA-DRA OT7KZMP2 moderate Genetic Variation [3]
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References

1 Protective effect of intravitreal injection of vasoactive intestinal peptide-loaded liposomes on experimental autoimmune uveoretinitis.J Ocul Pharmacol Ther. 2009 Feb;25(1):9-21. doi: 10.1089/jop.2008.0074.
2 Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.Clin Exp Immunol. 2017 Dec;190(3):293-303. doi: 10.1111/cei.13021. Epub 2017 Aug 30.
3 New insights into the genetic component of non-infectious uveitis through an Immunochip strategy.J Med Genet. 2017 Jan;54(1):38-46. doi: 10.1136/jmedgenet-2016-104144. Epub 2016 Sep 8.