Details of Disease

Disease Name

infective diarrhoea; infective diarrhea; infectious diarrhoea; infectious diarrheal diseases; infectious diarrheal disease; infectious diarrhea; dysenteric diarrhoea; dysenteric diarrhea; diarrheal disease, infectious

Definition

Acute inflammation of the intestine associated with infectious diarrhea of various etiologies, generally acquired by eating contaminated food containing toxins, biological derived from bacteria or other microorganisms. Dysentery is characterized initially by watery feces then by bloody mucoid stools. It is often associated with abdominal pain; fever; and dehydration.

Disease Hierarchy

DISXJSN4: Inflammatory diarrhea

DISVH6GQ: Acute diarrhea

DISE1NRW: Intestinal infectious disease

DISQRVLK: Diarrhea

DISEM33Q: Infectious disease

DISKICS2: Dysentery

Disease Identifiers

MONDO ID

MONDO_0001517

MESH ID

D004403

UMLS CUI

C0013369

MedGen ID

3934

SNOMED CT ID

19213003

General Information of Disease (ID: DISKICS2)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Ampicillin	DMHWE7P	Approved	Small molecular drug	[1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
LCT	TTA0OSE	Strong	Biomarker	[2]
MME	TT5TKPM	Strong	Therapeutic	[3]
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References

1	Ampicillin FDA Label
2	Comparative effects of osmotic and secretory diarrhoea on brush-border disaccharide hydrolases in rat.Afr J Med Med Sci. 2004 Dec;33(4):293-8.
3	Naloxone-reversible antidiarrheal effects of enkephalinase inhibitors.Eur J Pharmacol. 1987 Dec 1;144(2):125-32. doi: 10.1016/0014-2999(87)90510-3.