Details of Disease

General Information of Disease (ID: DISKM0P1)

• Disease Name: Immunoproliferative disorder
• Synonyms: Disorders, Immunoproliferative; Immunoproliferative Disorder; Immunoproliferative disorder; Immunoproliferative disease; Immunoproliferative Disorders; Disorder, Immunoproliferative; immunoproliferative disorder
• Disease Class: 2B32: Immunoproliferative disorder
• Definition: Disorders characterized by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins.
• Disease Hierarchy:
  DISAEGPH: Immune system disorder
  DISKM0P1: Immunoproliferative disorder
• ICD Code:
  ICD-11: ICD-11: 2B32
  ICD-10: ICD-10: D47.9
• Disease Identifiers:
  MONDO ID: MONDO_0021334
  MESH ID: D007160
  UMLS CUI: C0021070
  MedGen ID: 7038
  SNOMED CT ID: 1162658009

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 5 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
CAR.CD30 cells	DM6ZXWY	Phase 1/2	CAR T Cell Therapy	[1]
ATLCAR.CD30 cells	DMZI4UX	Phase 1	CAR T Cell Therapy	[2]
ATLCAR.CD30.CCR4 cells	DM3IPSX	Phase 1	CAR T Cell Therapy	[2]
IC9-CAR19 cells	DMP1ZF8	Phase 1	CAR T Cell Therapy	[3]
IC9-CAR19 T cells	DMNCBIU	Phase 1	CAR T Cell Therapy	[4]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] ClinicalTrials.gov (NCT02663297) Administration of T Lymphocytes for Prevention of Relapse of Lymphomas
• [2] ClinicalTrials.gov (NCT03602157) Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and NHL
• [3] ClinicalTrials.gov (NCT03016377) Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia
• [4] ClinicalTrials.gov (NCT03696784) Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma