Details of Disease | DrugMAP

General Information of Disease (ID: DISMCSDG)

Disease Name	Candidiasis, familial, 8
Synonyms	candidiasis, familial chronic mucocutaneous, autosomal recessive; CANDF8; TRAF3IP2 chronic mucocutaneous candidiasis (disease); chronic mucocutaneous candidiasis (disease) caused by mutation in TRAF3IP2; candidiasis, familial, 8; candidiasis, familial, type 8
Definition	Any chronic mucocutaneous candidiasis in which the cause of the disease is a mutation in the TRAF3IP2 gene.
Disease Hierarchy	DISPSGYF: Chronic mucocutaneous candidiasis DISMCSDG: Candidiasis, familial, 8
Disease Identifiers	MONDO ID MONDO_0014230 UMLS CUI C3714992 OMIM ID 615527 MedGen ID 811541

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
TRAF3IP2	OTLLZERL	Strong	Autosomal recessive	[1]
------------------------------------------------------------------------------------

References

1	Deficiency of Act1, a critical modulator of B cell function, leads to development of Sj?gren's syndrome. Eur J Immunol. 2008 Aug;38(8):2219-28. doi: 10.1002/eji.200738113.