Details of Disease

General Information of Disease (ID: DISNFZKJ)

Disease Name Adrenal gland cancer
Synonyms
tumour of the adrenal gland; tumor of the adrenal gland; adrenal neoplasm; malignant tumour of the adrenal gland; malignant tumour of adrenal gland; malignant tumor of the adrenal gland; malignant tumor of adrenal gland; malignant neoplasm of the adrenal gland; malignant neoplasm of adrenal gland; malignant adrenal tumour; malignant adrenal tumor; malignant adrenal neoplasm; malignant adrenal gland tumour; malignant adrenal gland tumor; malignant adrenal gland neoplasm; cancer of adrenal gland; adrenal gland cancer; adrenal cancer
Definition A malignant neoplasm involving the adrenal gland
Disease Hierarchy
DISAT1Z9: Advanced cancer
:
DISKTBM1: Malignant endocrine neoplasm
DISFK7RF: Adrenal gland neoplasm
DISNFZKJ: Adrenal gland cancer
Disease Identifiers
MONDO ID
MONDO_0002817
MESH ID
D000310
UMLS CUI
C0750887
MedGen ID
152909
SNOMED CT ID
363355002

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 5 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CDKN2A TTFTWQ8 Strong Biomarker [1]
GNRH1 TT0ID4A Strong Therapeutic [2]
GNRHR TT8R70G Strong Biomarker [3]
PRKACA TT5U49F Strong Biomarker [1]
TSHR TT6NYJA Strong Biomarker [3]
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This Disease Is Related to 3 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
CDC42 OT5QBC5M Strong Biomarker [1]
GNAS OTMH8BKJ Strong Biomarker [1]
RB1 OT9VMY7B Strong Biomarker [1]
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References

1 Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors.Nat Genet. 2014 Jun;46(6):613-7. doi: 10.1038/ng.2956. Epub 2014 Apr 20.
2 Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter. Endocr Relat Cancer. 2009 Jun;16(2):549-64. doi: 10.1677/ERC-08-0232. Epub 2009 Mar 4.
3 Screening for membrane hormone receptor expression in primary aldosteronism.Eur J Endocrinol. 2009 Mar;160(3):443-51. doi: 10.1530/EJE-08-0711. Epub 2009 Jan 8.