Details of Disease

General Information of Disease (ID: DISOV9GB)

Disease Name	Atrophic vaginitis
Synonyms	senile vaginitis; atrophic vaginitis
Disease Class	GA30: Menopausal disorder
Definition	Inflammation of the vagina due to thinning of the vaginal wall and decreased lubrication associated with reduced estrogen levels at menopause.
Disease Hierarchy	DISCYOMR: Vaginitis DISOV9GB: Atrophic vaginitis
ICD Code	ICD-11 ICD-11: GA30.2 ICD-10 ICD-10: N95.2 ICD-9 ICD-9: 627.3 Expand ICD-11 'GA30.2 Expand ICD-10 'N95.2 Expand ICD-9 627.3
Disease Identifiers	MONDO ID MONDO_0001410 MESH ID D059268 UMLS CUI C0156409 MedGen ID 510282 SNOMED CT ID 52441000

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Dienestrol	DMBSXI0	Approved	Small molecular drug	[1]
Estrone sulfate	DMVBIZL	Approved	Small molecular drug	[2]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ERCC8	OT0T4WKI	Strong	Biomarker	[3]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7160).
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3	Chitosan Ascorbate Nanoparticles for the Vaginal Delivery of Antibiotic Drugs in Atrophic Vaginitis.Mar Drugs. 2017 Oct 19;15(10):319. doi: 10.3390/md15100319.