Details of Disease | DrugMAP

General Information of Disease (ID: DISPGJPH)

Disease Name	Autosomal dominant vibratory urticaria
Synonyms	vibratory angioedema; angioedema, vibratory; VBU; vibratory urticaria, autosomal dominant; dermodistortive urticaria; DDU
Definition	An autosomal dominant disease characterized by localized hives and systemic manifestations in response to dermal vibration, with coincident degranulation of mast cells and increased histamine levels in serum.
Disease Hierarchy	DIS22GGG: Vibratory urticaria DIS3HIWD: Autosomal dominant disease DISSCALK: Hereditary skin disorder DISPGJPH: Autosomal dominant vibratory urticaria

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ADGRE2	OTUYJVYG	Supportive	Autosomal dominant	[1]
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References

1	Vibratory Urticaria Associated with a Missense Variant in ADGRE2. N Engl J Med. 2016 Feb 18;374(7):656-63. doi: 10.1056/NEJMoa1500611. Epub 2016 Feb 3.