Details of Disease

General Information of Disease (ID: DISRONZE)

Disease Name	Spinal stenosis
Synonyms	spinal stenosis of lumbar region; cervical spinal stenosis; lumbar spinal stenosis
Disease Class	FA82: Spinal stenosis
Definition	Narrowing of the spinal canal.
Disease Hierarchy	DISQRITY: Spinal disease DISO4AOQ: Disease of bone structure DISRONZE: Spinal stenosis
ICD Code	ICD-11 ICD-11: FA82 ICD-10 ICD-10: M48.0 Expand ICD-11 'FA82 Expand ICD-10 'M48.0
Disease Identifiers	MONDO ID MONDO_0005965 UMLS CUI C1861329 MedGen ID 396107 HPO ID HP:0003416

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Limaprost	DMDA3G2	Approved	Small molecular drug	[1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
KIF21A	OT511XD9	Strong	Biomarker	[2]
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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	A Japanese family with FEOM1-linked congenital fibrosis of the extraocular muscles type 1 associated with spinal canal stenosis and refinement of the FEOM1 critical region.Neuromuscul Disord. 2003 Aug;13(6):472-8. doi: 10.1016/s0960-8966(03)00065-8.