Details of Disease | DrugMAP

General Information of Disease (ID: DIST0BXW)

Disease Name	Anemia, hypochromic microcytic with iron overload
Synonyms	anemia, hypochromic microcytic, with iron overload
Disease Hierarchy	DIS0RMTQ: Hypochromic microcytic anemia DISYKSRF: Genetic disease DIST0BXW: Anemia, hypochromic microcytic with iron overload
Disease Identifiers	MONDO ID MONDO_0000104 MESH ID C567144 UMLS CUI C2673913 MedGen ID 388759 SNOMED CT ID 711161006

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
SLC11A2	TT2IS7P	Strong	Genetic Variation	[1]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CHMP2B	OTZA7RJB	Strong	Genetic Variation	[1]
DMRT1	OT5PU9U1	Strong	Genetic Variation	[1]
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References

1	A novel N491S mutation in the human SLC11A2 gene impairs protein trafficking and in association with the G212V mutation leads to microcytic anemia and liver iron overload.Blood Cells Mol Dis. 2011 Dec 15;47(4):243-8. doi: 10.1016/j.bcmd.2011.07.004. Epub 2011 Aug 26.