Details of Disease

General Information of Disease (ID: DISTB3ML)

• Disease Name: Photosensitivity disease
• Synonyms: disorders, photosensitivity; photodermatitides; disorder, photosensitivity; photodermatitis; photodermatosis; photosensitization; photosensitivity disorder
• Definition: Abnormal responses to sunlight or artificial light due to extreme reactivity of light-absorbing molecules in tissues. It refers almost exclusively to skin photosensitivity, including sunburn, reactions due to repeated prolonged exposure in the absence of photosensitizing factors, and reactions requiring photosensitizing factors such as photosensitizing agents and certain diseases. With restricted reference to skin tissue, it does not include photosensitivity of the eye to light, as in photophobia or photosensitive epilepsy.
• Disease Hierarchy:
  DIS9NUJ1: Radiodermatitis
  DISTB3ML: Photosensitivity disease
• Disease Identifiers:
  MONDO ID: MONDO_0006597
  MESH ID: D010787
  UMLS CUI: C0031762
  MedGen ID: 19281
  SNOMED CT ID: 22649008

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
FERMT1	OT626PBA	Strong	Genetic Variation	[1]

References

• [1] Recurrent mutations in kindlin-1, a novel keratinocyte focal contact protein, in the autosomal recessive skin fragility and photosensitivity disorder, Kindler syndrome.J Invest Dermatol. 2004 Jan;122(1):78-83. doi: 10.1046/j.0022-202X.2003.22136.x.