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Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
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Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis.Cancer Res. 2018 Mar 15;78(6):1484-1496. doi: 10.1158/0008-5472.CAN-17-1518. Epub 2018 Jan 12.
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Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis.J Natl Cancer Inst. 2011 Sep 7;103(17):1323-37. doi: 10.1093/jnci/djr290. Epub 2011 Aug 10.
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URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.Biochim Biophys Acta. 2003 Apr 17;1637(3):207-16. doi: 10.1016/s0925-4439(03)00035-8.
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The Effect of FERMT1 Regulated by miR-24 on the Growth and Radiation Resistance of Esophageal Cancer.J Biomed Nanotechnol. 2019 Mar 1;15(3):621-631. doi: 10.1166/jbn.2019.2711.
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Chronic colitis due to an epithelial barrier defect: the role of kindlin-1 isoforms.J Pathol. 2007 Dec;213(4):462-70. doi: 10.1002/path.2253.
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Digital transcript profile analysis with aRNA-LongSAGE validates FERMT1 as a potential novel prognostic marker for colon cancer.Clin Cancer Res. 2011 May 1;17(9):2908-18. doi: 10.1158/1078-0432.CCR-10-2552. Epub 2011 Jan 10.
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FERMT1 mediates epithelial-mesenchymal transition to promote colon cancer metastasis via modulation of -catenin transcriptional activity.Oncogene. 2017 Mar 30;36(13):1779-1792. doi: 10.1038/onc.2016.339. Epub 2016 Sep 19.
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Focal adhesion molecule Kindlin-1 mediates activation of TGF- signaling by interacting with TGF-RI, SARA and Smad3 in colorectal cancer cells.Oncotarget. 2016 Nov 15;7(46):76224-76237. doi: 10.18632/oncotarget.12779.
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Focal adhesions in the skin: lessons learned from skin fragility disorders.Eur J Dermatol. 2017 Jun 1;27(S1):8-11. doi: 10.1684/ejd.2017.3039.
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Expression of Kindlin-1 in human hepatocellular carcinoma and its prognostic significance.Tumour Biol. 2015 Jun;36(6):4235-41. doi: 10.1007/s13277-015-3060-8. Epub 2015 Jan 16.
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Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.Nat Genet. 2017 Feb;49(2):256-261. doi: 10.1038/ng.3760. Epub 2017 Jan 9.
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Kindlin-1 expression is involved in migration and invasion of pancreatic cancer.Int J Oncol. 2013 Apr;42(4):1360-6. doi: 10.3892/ijo.2013.1838. Epub 2013 Feb 22.
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Recurrent mutations in kindlin-1, a novel keratinocyte focal contact protein, in the autosomal recessive skin fragility and photosensitivity disorder, Kindler syndrome.J Invest Dermatol. 2004 Jan;122(1):78-83. doi: 10.1046/j.0022-202X.2003.22136.x.
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FERMT1 promoter mutations in patients with Kindler syndrome.Clin Genet. 2015 Sep;88(3):248-54. doi: 10.1111/cge.12490. Epub 2014 Oct 7.
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Kindlin-1 protects cells from oxidative damage through activation of ERK signalling.Free Radic Biol Med. 2017 Jul;108:896-903. doi: 10.1016/j.freeradbiomed.2017.05.013. Epub 2017 May 10.
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KIND1 Loss Sensitizes Keratinocytes to UV-Induced Inflammatory Response and DNA Damage.J Invest Dermatol. 2017 Feb;137(2):475-483. doi: 10.1016/j.jid.2016.09.023. Epub 2016 Oct 7.
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Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.PLoS Genet. 2008 Dec;4(12):e1000289. doi: 10.1371/journal.pgen.1000289. Epub 2008 Dec 5.
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Kindlin-1 Regulates Astrocyte Activation and Pain Sensitivity in Rats With Neuropathic Pain.Reg Anesth Pain Med. 2018 Jul;43(5):547-553. doi: 10.1097/AAP.0000000000000780.
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Prognostic implications of Kindlin proteins in human osteosarcoma.Onco Targets Ther. 2017 Feb 7;10:657-665. doi: 10.2147/OTT.S125418. eCollection 2017.
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A novel large deletion mutation of FERMT1 gene in a Chinese patient with Kindler syndrome.J Zhejiang Univ Sci B. 2015 Nov;16(11):957-62. doi: 10.1631/jzus.B1500080.
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Evaluating KIND1 human embryonic stem cell-derived pancreatic progenitors to ameliorate streptozotocin-induced diabetes in mice.Indian J Med Res. 2017 Aug;146(2):244-254. doi: 10.4103/ijmr.IJMR_210_16.
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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Arch Toxicol. 2013 Jan;87(1):123-43.
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Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.
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Bringing in vitro analysis closer to in vivo: studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling. Toxicol Lett. 2018 Sep 15;294:184-192.
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Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper. Physiol Genomics. 2009 Aug 7;38(3):386-401.
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Activation of AIFM2 enhances apoptosis of human lung cancer cells undergoing toxicological stress. Toxicol Lett. 2016 Sep 6;258:227-236.
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Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells. Mutagenesis. 2011 Sep;26(5):593-604.
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Temozolomide induces activation of Wnt/-catenin signaling in glioma cells via PI3K/Akt pathway: implications in glioma therapy. Cell Biol Toxicol. 2020 Jun;36(3):273-278. doi: 10.1007/s10565-019-09502-7. Epub 2019 Nov 22.
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Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation. PLoS One. 2012;7(12):e53003. doi: 10.1371/journal.pone.0053003. Epub 2012 Dec 27.
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Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst. 2009 Mar 4;101(5):306-20.
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Progesterone regulation of implantation-related genes: new insights into the role of oestrogen. Cell Mol Life Sci. 2007 Apr;64(7-8):1009-32.
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Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. Toxicol Sci. 2010 Apr;114(2):193-203. doi: 10.1093/toxsci/kfp309. Epub 2009 Dec 31.
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A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
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Ethyl carbamate induces cell death through its effects on multiple metabolic pathways. Chem Biol Interact. 2017 Nov 1;277:21-32.
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Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study. Oncotarget. 2017 Jan 3;8(1):1369-1391. doi: 10.18632/oncotarget.13622.
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CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer. J Clin Invest. 2016 Feb;126(2):639-52.
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Cell-based two-dimensional morphological assessment system to predict cancer drug-induced cardiotoxicity using human induced pluripotent stem cell-derived cardiomyocytes. Toxicol Appl Pharmacol. 2019 Nov 15;383:114761. doi: 10.1016/j.taap.2019.114761. Epub 2019 Sep 15.
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Quantitative phosphoproteomics reveal cellular responses from caffeine, coumarin and quercetin in treated HepG2 cells. Toxicol Appl Pharmacol. 2022 Aug 15;449:116110. doi: 10.1016/j.taap.2022.116110. Epub 2022 Jun 7.
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Bisphenol A and bisphenol S induce distinct transcriptional profiles in differentiating human primary preadipocytes. PLoS One. 2016 Sep 29;11(9):e0163318.
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From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch Toxicol. 2014 Jul;88(7):1451-68.
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Transcriptional profiling of lactic acid treated reconstructed human epidermis reveals pathways underlying stinging and itch. Toxicol In Vitro. 2019 Jun;57:164-173.
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Transcriptomic analysis of human primary bronchial epithelial cells after chloropicrin treatment. Chem Res Toxicol. 2015 Oct 19;28(10):1926-35.
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The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel. BMC Med Genomics. 2010 Aug 13;3:37. doi: 10.1186/1755-8794-3-37.
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