Details of Disease

General Information of Disease (ID: DISV9HNG)

Disease Name Primary cutaneous amyloidosis
Synonyms
lichen amyloidosis familial; amyloidosis IX; amyloidosis, primary localised cutaneous; amyloidosis, primary localized cutaneous; amyloidosis familial cutaneous lichen; familial primary localized cutaneous amyloidosis; familial primary localised cutaneous amyloidosis; PLCA; primary localised cutaneous amyloidosis; primary localized cutaneous amyloidosis
Definition
Cutaneous amyloidosis refers to a variety of skin diseases characterized histologically by the extracellular accumulation of amyloid deposits in the dermis. Rare forms include lichen amyloidosus, X-linked reticulate pigmentary disorder, primary localized cutaneous nodular amyloidosis, and macular amyloidosis.
Disease Hierarchy
DISHTAI2: Amyloidosis
DIS4SKIE: Dermis disorder
DISV9HNG: Primary cutaneous amyloidosis
Disease Identifiers
MONDO ID
MONDO_0015301
MESH ID
C562642
UMLS CUI
C0268397
MedGen ID
120635
HPO ID
HP:0012309
Orphanet ID
137807
SNOMED CT ID
733729003

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
OSMR TTAH0KM Strong Genetic Variation [1]
------------------------------------------------------------------------------------

References

1 Clinical and genetic features of Chinese patients with lichen and macular primary localized cutaneous amyloidosis.Clin Exp Dermatol. 2019 Jun;44(4):e110-e117. doi: 10.1111/ced.13925. Epub 2019 Feb 7.