Details of Disease

General Information of Disease (ID: DISW96AL)

• Disease Name: Growth failure
• Disease Class: LD2F: Multiple structural anomalies syndrome
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISW96AL: Growth failure
• ICD Code: ICD-11: ICD-11: LD2F.1Y
• Disease Identifiers: MedGen ID: 163904

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Lonapegsomatropin	DMPR8E9	Approved	NA	[1]
Mecasermin	DM1O3BY	Approved	NA	[2]

This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Albutropin	DMWAL73	Phase 3	NA	[3]
NN8640	DMBRZG7	Phase 3	NA	[4]
Vitatropin	DMHNFZ9	Phase 1	NA	[5]

This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
ARX-201	DMS0LCZ	Discontinued in Phase 2	NA	[6]

This Disease is Treated as An Indication in 3 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Azotropin	DMKCZTT	Investigative	NA	[7]
BBT-031	DM1G3B6	Investigative	NA	[7]
CKD-404	DM7QCSD	Investigative	NA	[7]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 761177.
• [2] Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
• [3] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016005)
• [4] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035582)
• [5] ClinicalTrials.gov (NCT01440686) Safety, Pharmacokinetics and Pharmacodynamics Study of HL-032 in Healthy Male Volunteers. U.S. National Institutes of Health.
• [6] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022324)
• [7] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.