Details of Disease

General Information of Disease (ID: DISYIW4H)

Disease Name Eosinophilic gastroenteritis
Synonyms EGE; eosinophilic gastroenteritis; eosinophilic enteritis; eosinophilic gastroenterocolitis
Definition
Eosinophilic gastroenteritis (EGE) is a rare benign gastrointestinal disease characterized by the presence of abnormal and nonspecific gastro-intestinal (GI) manifestations, associated with an eosinophilic infiltration of the GI tract, which can affect several segments and involve several layers within the GI wall.
Disease Hierarchy
DISZLHO0: Eosinophilic gastrointestinal disease
DISXQCG5: Gastroenteritis
DISYIW4H: Eosinophilic gastroenteritis
Disease Identifiers
MONDO ID
MONDO_0016129
MESH ID
C535952
UMLS CUI
C1262481
MedGen ID
220382
HPO ID
HP:0032064
Orphanet ID
2070
SNOMED CT ID
359804008

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
SIGLEC8 OTQ5TRRV Limited Biomarker [1]
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References

1 Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis.JCI Insight. 2019 Oct 3;4(19):e126219. doi: 10.1172/jci.insight.126219.