Details of Drug Off-Target (DOT)
General Information of Drug Off-Target (DOT) (ID: OT7BLO6L)
DOT Name | Late cornified envelope protein 1B (LCE1B) | ||||
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Synonyms | Late envelope protein 2; Small proline-rich-like epidermal differentiation complex protein 2A | ||||
Gene Name | LCE1B | ||||
UniProt ID | |||||
3D Structure | |||||
Pfam ID | |||||
Sequence |
MSCQQNQQQCQPPPKCIPKCPPKCLTPRCPPKCPPKCPPVSSCCSVSSGGCCGSSSGGSC
GSSSGGCCSSGGGGCCLSHHRRRRSHCHRPQSSGCCSQPSGGSSCCGGGSGQHSGGCC |
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Function | Precursors of the cornified envelope of the stratum corneum. | ||||
Tissue Specificity | Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta. | ||||
Reactome Pathway | |||||
Molecular Interaction Atlas (MIA) of This DOT
Molecular Interaction Atlas (MIA) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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6 Drug(s) Affected the Gene/Protein Processing of This DOT
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1 Drug(s) Affected the Post-Translational Modifications of This DOT
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References