Details of the Drug Combination

General Information of Drug Combination (ID: DC44ZU5)

Drug Combination Name

Dexmethylphenidate Dexmethylphenidate

Indication

Disease Entry	Status	REF
ADHD	Phase 3	[1]

Component Drugs

Dexmethylphenidate DMUQE2A

N.A.

2D MOL

3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)

Indication(s) of Dexmethylphenidate

Disease Entry	ICD 11	Status	REF
Attention deficit hyperactivity disorder	6A05.Z	Suspended	[]

Dexmethylphenidate Interacts with 1 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Carboxylesterase 1 (CES1)	DEB30C5	EST1_HUMAN	Metabolism	[2]
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Indication(s) of Dexmethylphenidate

Disease Entry	ICD 11	Status	REF
Attention deficit hyperactivity disorder	6A05.Z	Suspended	[]

Dexmethylphenidate Interacts with 1 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Carboxylesterase 1 (CES1)	DEB30C5	EST1_HUMAN	Metabolism	[2]
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Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
ADHD	DC9KTN8	N. A.	Phase 3	[1]
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References

1	ClinicalTrials.gov (NCT05286762) Phase 3 Efficacy and Safety Fixed-Dose Study in Pediatrics (6-17) With ADHD Using CTx-1301
2	Dexmethylphenidate hydrochloride in the treatment of attention deficit hyperactivity disorder. Neuropsychiatr Dis Treat. 2006 Dec;2(4):467-73.