General Information of This Drug (ID: DM4M1SG)

Drug Name
Clarithromycin   DM4M1SG
Synonyms
Abbotic; Adel; Astromen; Biaxin; Bicrolid; CTY; Clacine; Clambiotic; Claribid; Claricide; Clarith; Clarithromycina; Clarithromycine; Clarithromycinum; Claritromicina; Clathromycin; Cyllid; Cyllind; Helas; Heliclar; Klacid; Klaciped; Klaricid; Klarid; Klarin; Klax; Kofron; Mabicrol; Macladin; Maclar; Mavid; Naxy;Veclam; Zeclar; Biaxin HP; Biaxin XL; Biaxin filmtab; Biaxin xl filmtab; Clarithromycin extended release; Clarithromycin suspension or tablets; Klaricid Pediatric; Klaricid XL; TE031; A-56268; ANX-015; Abbott-56268; Biaxin (TN); Clacid (TN); Claridar (TN); Claripen (TN); Clarithromycine [INN-French]; Clarithromycinum [INN-Latin]; Claritromicina [INN-Spanish]; Crixan (TN); DRG-0099; Fromilid (TN);Infex (TN); Klabax (TN); Klaricid (TN); Klaricid H.P; Lactoferrin B & Clarithromycin; Lactoferrin H & Clarithromycin; SDP-015; TE-031; Vikrol (TN); CLM & IL-12; CRL-1605 & Clarithromycin; Clarithromycin & Interleukin-12; Klaricid H.P.; O(6)-methylerythromycin; Clarithromycin (JP15/USP/INN); Clarithromycin [USAN:INN:BAN:JAN]; Hydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexame; (14R)-14-Hydroxyclarithromycin; 6-O-Methylerythromycin; 6-O-Methylerythromycin a
Indication
Disease Entry ICD 11 Status REF
Acute maxillary sinusitis N.A. Approved [1]
Acute otitis media AB00 Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Mycoplasma pneumoniae pneumonia N.A. Approved [1]
Staphylococcus aureus infection N.A. Approved [1]
Streptococcal pneumonia N.A. Approved [1]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [3]
Pneumonia caused by chlamydia N.A. Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

57 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Clarithromycin + Metronidazole DC7FL3I Metronidazole Helicobacter Pylori Infection [4]
Clarithromycin + Esomeprazole DCB6MI5 Esomeprazole Helicobacter Pylori Infection [5]
Clarithromycin + Pantoprazole DCOMMIN Pantoprazole Helicobacter Pylori Infection [6]
Clarithromycin + Rabeprazole DCP9HTK Rabeprazole Helicobacter Pylori Infection [7]
Clarithromycin + Esomeprazole DC6QPNU Esomeprazole Helicobacter Pylori Infection [8]
Clarithromycin + Pantoprazole DCQ9MIX Pantoprazole Dyspepsia [9]
Clarithromycin + Colchicine DC7AJLZ Colchicine Pharmacokinetics [10]
Clarithromycin + Cefazolin DCMFEZ4 Cefazolin Preterm Premature Rupture of Membrane [11]
Clarithromycin + Pomalidomide DCSAHE5 Pomalidomide Multiple Myeloma [12]
Clarithromycin + Edivoxetine DCUACCN Edivoxetine Depressive Disorder, Major [13]
Clarithromycin + Potassium Citrate DCPTEJY Potassium Citrate Helicobacter Pylori [14]
Clarithromycin + Vonoprazan DC52MW8 Vonoprazan Helicobacter Pylori [15]
Clarithromycin + Pantoprazole DC8MTNA Pantoprazole Drug Interaction [16]
Clarithromycin + Esomeprazole DCIDFPG Esomeprazole Helicobacter Pylori [15]
Clarithromycin + Voriconazole DCWR1YI Voriconazole B-cell Malignancies [17]
Clarithromycin + Docetaxel DC0ZW7Z Docetaxel Prostate Cancer [18]
Clarithromycin + LY2835219 DC6IN7U LY2835219 Neoplasm [19]
Clarithromycin + Amoxicillin DC7PA0V Amoxicillin Drug Interaction [16]
Clarithromycin + Diltiazem DCDMQ8Y Diltiazem CLARITHROMYCIN/DILTIAZEM [VA Drug Interaction] [20]
Clarithromycin + ITF2357 DCIJMM2 ITF2357 Drug-Drug Interaction [21]
Clarithromycin + ITF2357 DCN2HZT ITF2357 Drug Drug Interaction [22]
Clarithromycin + Cabazitaxel DCOAWM2 Cabazitaxel Prostate Cancer [18]
Clarithromycin + Apixaban DCVWGS6 Apixaban Venous Thromboembolism [23]
Dexamethasone + Clarithromycin DC66OVY Dexamethasone Multiple Myeloma [12]
Dexlansoprazole + Clarithromycin DC8BV1J Dexlansoprazole Helicobacter Pylori Infection [24]
Omeprazole + Clarithromycin DC0MNTM Omeprazole Helicobacter Pylori Infection [25]
Rifampicin + Clarithromycin DC76VL2 Rifampicin Vitamin D and Calcium Homeostasis [26]
Bedaquiline + Clarithromycin DC066AG Bedaquiline Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD) [27]
Clarithromycin + Vonoprazan DC23ZIF Vonoprazan Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other [28]
Clarithromycin + Amoxicillin DC1GAFQ Amoxicillin Helicobacter Pylori Infection [29]
Clarithromycin + Amoxicillin DCF1IST Amoxicillin Acid Dyspepsia [30]
Dexamethasone + Clarithromycin DCHJSF0 Dexamethasone Multiple Myeloma [31]
Dexamethasone + Clarithromycin DCN1PZR Dexamethasone Relapse/Refractory Multiple Myeloma [32]
Dexamethasone + Clarithromycin DCQI3SJ Dexamethasone Multiple Myeloma [33]
Clarithromycin + Amoxicillin DC3BGTZ Amoxicillin Helicobacter Pylori Infection [34]
Clarithromycin + Clarithromycin DC6ZIB7 Clarithromycin Otitis Media [35]
Clarithromycin + Amoxicillin DC8N0YC Amoxicillin H. Pylori Infection [36]
Clarithromycin + Vonoprazan DCK6IOU Vonoprazan Helicobacter Pylori Infection [34]
Clarithromycin + Esomeprazole DCO0PI4 Esomeprazole Treatment Effectiveness [37]
Clarithromycin + Vonoprazan DCSNZ5N Vonoprazan Treatment Effectiveness [37]
Dexamethasone + Clarithromycin DCE49RJ Dexamethasone Multiple Myeloma [38]
Nitazoxanide + Clarithromycin DC6GJMF Nitazoxanide Helicobacter-associated Gastritis [39]
Rifampicin + Clarithromycin DCLFKJ7 Rifampicin Lung Infection [40]
Tindamax + Clarithromycin DCY6M25 Tindamax Helicobacter Infections [41]
Clarithromycin + Esomeprazole DC8ORUL Esomeprazole Helicobacter Pylori Infection [42]
Clarithromycin + Esomeprazole DC995M7 Esomeprazole Gastritis [43]
Clarithromycin + Metronidazole DCBVAFA Metronidazole Helicobacter Pylori Infection [44]
Clarithromycin + Esomeprazole DC05BRR Esomeprazole Helicobacter Pylori Infection [45]
Clarithromycin + Esomeprazole DC155DP Esomeprazole Functional Dyspepsia [46]
Clarithromycin + Esomeprazole DC2PC9B Esomeprazole Helicobacter Pylori Infection [47]
Clarithromycin + Metronidazole DC9K90S Metronidazole Peptic Ulcer [48]
Clarithromycin + Rabeprazole DCCFCI5 Rabeprazole Helicobacter Pylori Infection [49]
Clarithromycin + Metronidazole DCEORIT Metronidazole Helicobacter Pylori Infection [44]
Clarithromycin + Rabeprazole DCJ5WBT Rabeprazole Helicobacter Pylori Infection [49]
Clarithromycin + Amoxicillin DCQQMYT Amoxicillin Helicobacter Pylori Infection [50]
Clarithromycin + Amoxicillin DCEOFR6 Amoxicillin Peptic Ulcer [48]
Clarithromycin + Amoxicillin DCWZIOF Amoxicillin Antimicrobial Susceptibility Testing [51]
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⏷ Show the Full List of 57 DrugCom(s)

References

1 Clarithromycin FDA Label
2 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
3 Anti-inflammatory Clarithromycin for Improving COVID-19 Infection Early (ACHIEVE)
4 ClinicalTrials.gov (NCT05926804) A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile
5 ClinicalTrials.gov (NCT03383003) Comparison of Two Novel First-line Anti-Helicobacter Pylori Therapy
6 ClinicalTrials.gov (NCT04621487) Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection
7 ClinicalTrials.gov (NCT05152004) Efficacies of Hybrid and High-dose Dual Therapies for the First-line Anti-H Pylori Treatment
8 ClinicalTrials.gov (NCT05189444) The Evaluation of Triple Therapy With Vonoprazan, Amoxicillin and Bismuth for Eradication of Helicobacter Pylori
9 ClinicalTrials.gov (NCT04697641) Helicobacter Pylori Eradication in Functional Dyspepsia
10 ClinicalTrials.gov (NCT00984061) Drug-Drug Interaction Study of Colchicine and Clarithromycin
11 ClinicalTrials.gov (NCT01503606) Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane
12 ClinicalTrials.gov (NCT01745588) Autologous Stem Cell Transplant With Pomalidomide (CC-4047) Maintenance Versus Continuous Clarithromycin/ Pomalidomide / Dexamethasone Salvage Therapy in Relapsed or Refractory Multiple Myeloma
13 ClinicalTrials.gov (NCT01460407) A Study to Evaluate the Effect of Clarithromycin on LY2216684
14 ClinicalTrials.gov (NCT02892409) TAK-438 Bismuth Drug Interaction Study
15 ClinicalTrials.gov (NCT04753437) A Study of Vonoprazan in Adults With Helicobacter Pylori
16 ClinicalTrials.gov (NCT03011996) To Investigate PK and PD of CJ-12420, Clarithromycin, Amoxicillin After Multiple Dose Administration
17 ClinicalTrials.gov (NCT04551963) Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies
18 ClinicalTrials.gov (NCT03043989) Cohorts of Docetaxel or Cabazitaxel in Combination With the Potent CYP3A4 Inhibitor, Clarithromycin
19 ClinicalTrials.gov (NCT02117648) A Study of LY2835219 in Participants With Cancer
20 ClinicalTrials.gov (NCT02080780) Study to Evaluate the Interaction Potential of Clarithromycin XL on Diltiazem Hydrochloride Cream 2% in Healthy Subjects
21 ClinicalTrials.gov (NCT05492318) Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity
22 ClinicalTrials.gov (NCT05845567) The Potential of Givinostat as DDI Victim in Co-administration P-gp Inhibitor (Part 2)
23 ClinicalTrials.gov (NCT02912234) Effect of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Participants
24 ClinicalTrials.gov (NCT03829150) Dexlansoprazole MR-Based Concomitant Quadruple Therapy
25 ClinicalTrials.gov (NCT01593592) Lactobacillus Reuteri in Management of Helicobacter Pylori Infection in Dyspeptic Patients
26 ClinicalTrials.gov (NCT02019875) CYP3A4 Activity and Mineral Homeostasis
27 ClinicalTrials.gov (NCT04630145) A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)
28 ClinicalTrials.gov (NCT03219723) Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"
29 ClinicalTrials.gov (NCT05861687) Recurrence Rate Comparison Between Esomeprazole and Lansoprazole in Eradicating Helicobacter Pylori Infection Among Children
30 ClinicalTrials.gov (NCT03428568) Safety Trial of Herbal Melanin in Gastritis Patients
31 ClinicalTrials.gov (NCT01374217) Administration of Tadalafil in Conjunction With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma
32 ClinicalTrials.gov (NCT02986451) Clarithromycin,Lenalidomide and Dexamethasone for Relapsed/Refractory Myeloma
33 ClinicalTrials.gov (NCT01159574) Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma
34 ClinicalTrials.gov (NCT04167670) Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection
35 ClinicalTrials.gov (NCT04016051) Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections
36 ClinicalTrials.gov (NCT01505127) Efficacy of TAK-438, Amoxicillin and Clarithromycin in the First Line Eradication of H. Pylori
37 ClinicalTrials.gov (NCT06162949) Vonoprazan for Helicobacter Pylori Eradication in Adolescents
38 ClinicalTrials.gov (NCT02516696) BiRd vs. Rd as Initial Therapy in Multiple Myeloma
39 ClinicalTrials.gov (NCT02422706) Study of Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori
40 ClinicalTrials.gov (NCT03236987) CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections
41 ClinicalTrials.gov (NCT04652284) Effectiveness of Rifabutin for Treatment of Helicobacter Pylori
42 ClinicalTrials.gov (NCT04090021) Genotypic Resistance-guided Versus Empirical Therapy for H. Pylori Eradication.
43 ClinicalTrials.gov (NCT02296021) Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Bismuth-containing Quadruple Therapy
44 ClinicalTrials.gov (NCT03130452) Helicobacter Pylori Eradication Study
45 ClinicalTrials.gov (NCT02732249) Clarithromycin Triple Therapy Plus Bismuth for Helicobacter Pylori First-line Treatment
46 ClinicalTrials.gov (NCT01667575) Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pylori
47 ClinicalTrials.gov (NCT02552641) Food Effect on the Eradication Rate of H. Pylori With Triple Therapy With Esomeprazole
48 ClinicalTrials.gov (NCT02648659) The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patients
49 ClinicalTrials.gov (NCT05061732) Helicobacter Pylori Eradication and Follow-up
50 ClinicalTrials.gov (NCT03124420) Intraluminal Therapy for Helicobacter Pylori Infection
51 ClinicalTrials.gov (NCT03139253) Antimicrobial Susceptibility Testing Guided Triple Therapy in Salvage Helicobacter Pylori Treatment