Details of the Drug Combinations

General Information of This Drug (ID: DM5PVQE)

Drug Name

Paroxetine DM5PVQE

Synonyms

Seroxat (TN)

Indication

Disease Entry	ICD 11	Status	REF
Anxiety disorder	6B00-6B0Z	Approved	[1]
Depression	6A70-6A7Z	Approved	[2]
Hot flushes	GA30	Approved	[1]
Major depressive disorder	6A70.3	Approved	[1]
Obsessive compulsive disorder	6B20	Approved	[1]
Panic disorder	6B01	Approved	[1]
Post-traumatic stress disorder	6B40	Approved	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of Indication(s)

Therapeutic Class

Antidepressants

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

10 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Paroxetine + Mirtazapine	DCHPYDT	Mirtazapine	Major Depression	[3]
Paroxetine + Saredutant	DCNVROM	Saredutant	Depressive Disorder, Major	[4]
Paroxetine + Naltrexone	DCO3W41	Naltrexone	Alcoholism	[5]
Paroxetine + Lamotrigine	DCVGW2X	Lamotrigine	Unipolar Depression	[6]
Paroxetine + Paroxetine	DCIKKUK	Paroxetine	Depressive Disorder	[7]
Quetiapine + Paroxetine	DCF9I9G	Quetiapine	Combat Disorders	[8]
Paroxetine + Telaprevir	DCB8C11	Telaprevir	Hepatitis C Infection	[9]
Methotrexate + Paroxetine	DCPUUM8	Methotrexate	Rheumatoid Arthritis	[10]
Paroxetine + Pregabalin	DCUVLDM	Pregabalin	Burning Mouth Syndrome	[11]
Paroxetine + Buspirone	DCC96C6	Buspirone	Major Depression Disorder	[12]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 DrugCom(s)

References

1	Paroxetine FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4790).
3	ClinicalTrials.gov (NCT01458626) Effectiveness Study of Mirtazapine Combined With Paroxetine in Major Depressive Patients Without Early Improvement
4	ClinicalTrials.gov (NCT00629551) An Eight-week Study of Saredutant and Paroxetine as Combination Treatment for Major Depressive Disorder
5	ClinicalTrials.gov (NCT00338962) Naltrexone & SSRI in Alcoholics With Depression/PTSD
6	ClinicalTrials.gov (NCT00901407) Lamotrigine Augmentation in Resistant Depression
7	ClinicalTrials.gov (NCT00938184) Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects
8	ClinicalTrials.gov (NCT00292370) Quetiapine Augmentation for Treatment-resistant PTSD
9	ClinicalTrials.gov (NCT01841502) Interaction Between Paroxetine and Telaprevir
10	ClinicalTrials.gov (NCT06231745) Paroxetine Safety and Efficacy in Rheumatoid Arthritis
11	ClinicalTrials.gov (NCT06025474) Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome
12	ClinicalTrials.gov (NCT02273154) RandomizedControlled and Open-label Study of Buspirone add-on Treatment in Patients With Major Depression Disorder