General Information of This Drug (ID: DMB4AVP)

Drug Name
Pamidronate   DMB4AVP
Synonyms
AHPrBP; Amidronate; Aminomux; Aminopropanehydroxydiphosphonate; Aredia; Ribodroat; Acide pamidronique; Acido pamidronico; Acidum pamidronicum; Aminohydroxypropylidene diphosphonate; Novartis brand of pamidronate disodium salt; PAMIDRONATE DISODIUM; PAMIDRONIC ACID; Pamidronate calcium; Pamidronate monosodium; Bisphosphonate 6; Acide pamidronique [INN-French]; Acido pamidronico [INN-Spanish]; Acidum pamidronicum [INN-Latin]; Pamidronic acid (INN); Pamidronic acid [INN:BAN]; Ribodroat (TN); Amino-1-hydroxypropane-1,1-diphosphonate; (3-AMINO-1-HYDROXY-1-PHOSPHONO-PROPYL)PHOSPHONIC ACID; (3-Amino-1-hydroxypropylidene)bisphosphonic acid; (3-Amino-1-hydroxypropylidene)diphosphonic acid; (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid; (3-amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid); (3-amino-1-hydroxypropylidene)-1,1-biphosphonate; (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate; 1-hydroxy-3-aminopropane-1,1-diphosphonic acid; 3-Amino-1-hydroxypropylidene-1,1-diphosphonate
Indication
Disease Entry ICD 11 Status REF
Bone Paget disease N.A. Approved [1]
Hypercalcaemia 5B91.0 Approved [2]
Therapeutic Class
Antiinflammatory Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

43 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acetohexamide + Pamidronate DC4X8JS Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acitretin + Pamidronate DCQ5PJ9 Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Arfolitixorin + Pamidronate DCW425L Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Pamidronate DCFYM3F Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BIO-300 + Pamidronate DCR5RHE BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Pamidronate DCTN5N4 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Pamidronate DCX9ERF Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Docetaxel + Pamidronate DCY32ER Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fomepizole + Pamidronate DCFMBW4 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fosfomycin + Pamidronate DCWK2ON Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
IT-141 + Pamidronate DCMP0PS IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Kanamycin + Pamidronate DCRL085 Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Leflunomide + Pamidronate DCDC2H6 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Pamidronate DC4HWKK Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methylene blue + Pamidronate DCDRJ27 Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Pamidronate DCIWIZ6 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Pamidronate DCAH7MW Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oxyphenbutazone + Pamidronate DC7WWKT Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Gefitinib DCVP4WD Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Isosorbide dinitrate DC25RWD Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Efavirenz DCH4V9A Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Chlorzoxazone DCJVSKA Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Pentamidine DCOQ3SB Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Diazoxide DCK9SGU Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Entacapone DC3NL2D Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Imatinib DCXS1N2 Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Probenecid DCSKRA1 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Darunavir DC1YGJN Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Bortezomib DCPTOUY Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Maprotiline DCY8H77 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Quinine DCJ8X55 Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + PMID28870136-Compound-43 DC1XN1R PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + FORMESTANE DC5TH7B FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Vorinostat DC8866Q Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + AS-1949490 DC9LQVY AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PF-02545920 + Pamidronate DCHEXDD PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Picoplatin + Pamidronate DCE7ZE0 Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pyrazinamide + Pamidronate DCC6C0N Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sitagliptin + Pamidronate DCUSBEL Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Terameprocol + Pamidronate DCZA34V Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triflupromazine + Pamidronate DCVQ9YS Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Pamidronate DC0KH12 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tropisetron + Pamidronate DCVQYBW Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 43 DrugCom(s)
1 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Pamidronate + Zoledronate DCBVMXD Zoledronate Multiple Myeloma and Plasma Cell Neoplasm [4]
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References

1 Pamidronate FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7259).
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT00482378) Samarium Sm 153 Lexidronam Pentasodium Combined With Zoledronic Acid or Pamidronate in Treating Patients With Relapsed or Refractory Multiple Myeloma and Bone Pain