Details of the Drug Combinations

General Information of This Drug (ID: DMBP5N3)

Drug Name
Cantharidin   DMBP5N3
Synonyms
DSSTox_CID_21752; DSSTox_RID_79835; DSSTox_GSID_41752; CAS-56-25-7; NCGC00016247-01; Spectrum_001114; SpecPlus_000537; Spectrum4_000920; Spectrum2_000630; Prestwick0_000885; Spectrum3_000621; Prestwick1_000885; Spectrum5_001618; Prestwick2_000885; KBioSS_001594; KBioGR_001420; BSPBio_002182; MLS002153505; SCHEMBL152261; DivK1c_006633; SPBio_002889; SPBio_000600; CHEMBL299846; DTXSID7041752; KBio2_006730; KBio3_001682; KBio2_004162; KBio2_001594; KBio1_001577; MolPort-003-665-556; HMS1570B12; Tox21_110326; CCG-39927; Tox21_110326_1
Indication
Disease Entry ICD 11 Status REF
Molluscum contagiosum infection 1E76 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

29 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
(-)-englerin A + Cantharidin DCNV0RE (-)-englerin A Ewing sarcoma (Cell Line: TC-71) [2]
ABT-263 + Cantharidin DC6DJ3E ABT-263 Ewing sarcoma (Cell Line: TC-71) [3]
BMS-754807 + Cantharidin DCR74YS BMS-754807 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
CA4P + Cantharidin DCV9U6W CA4P Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
Cantharidin + Ym155 DCQTLP0 Ym155 Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + SCH-900776 DC0D0GA SCH-900776 Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + AZD8055 DCBI5UW AZD8055 Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + Everolimus DCGYZK0 Everolimus Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + THAPSIGARGIN DCKZCV8 THAPSIGARGIN Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + Etoposide DCYGQUS Etoposide Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + PHA-739358 DCOKDPI PHA-739358 Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + OSI-906 DC0278D OSI-906 Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + Pelitinib DC9KRHM Pelitinib Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + Cabozantinib DC8FXHY Cabozantinib Ewing sarcoma (Cell Line: TC-71) [2]
Cantharidin + Ciclopirox DCH3KF4 Ciclopirox Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
Cantharidin + LY2874455 DC5L5CG LY2874455 Ewing sarcoma (Cell Line: TC-71) [2]
Chloroquine + Cantharidin DCDO4VY Chloroquine Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
Chloroxine + Cantharidin DC92I69 Chloroxine Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
Dasatinib + Cantharidin DCC3DJ7 Dasatinib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
Fostamatinib + Cantharidin DCVPUTE Fostamatinib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
GDC-0980/RG7422 + Cantharidin DCFGIFJ GDC-0980/RG7422 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
IMD-0354 + Cantharidin DCY9YSJ IMD-0354 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
JQ1 + Cantharidin DCL3Y4P JQ1 Ewing sarcoma (Cell Line: TC-71) [2]
NVP-AUY922 + Cantharidin DCMW68D NVP-AUY922 Ewing sarcoma (Cell Line: TC-71) [2]
PF-04691502 + Cantharidin DCTKB59 PF-04691502 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
Raloxifene + Cantharidin DCVYTAP Raloxifene Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
SNX-5422 + Cantharidin DCK8TO1 SNX-5422 Ewing sarcoma (Cell Line: TC-71) [2]
THAPSIGARGIN + Cantharidin DCBGZCT THAPSIGARGIN Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [2]
Trametinib + Cantharidin DCFH778 Trametinib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
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⏷ Show the Full List of 29 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.