Details of the Drug Combinations

General Information of This Drug (ID: DMG0OUD)

Drug Name
GS4071   DMG0OUD
Synonyms
Oseltamivir acid; 187227-45-8; Oseltamivir carboxylate; Oseltamivir (acid); GS 4071; Ro 64-0802; UNII-K6106LV5Q8; CHEMBL674; CHEBI:73139; K6106LV5Q8; GS-4071; (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid; 5-N-ACETYL-3-(1-ETHYLPROPYL)-1-CYCLOHEXENE-1-CARBOXYLIC ACID; 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)-; (3r,4r,5s)-4-(Acetylamino)-5-Amino-3-(Pentan-3-Yloxy)cyclohex-1-Ene-1-Carboxylic Acid; G39; Oseltamivir-carboxylate; 2,4-diamino triazine
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

32 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Brincidofovir + GS4071 DC4X2FO Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + GS4071 DC8IX1Z Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dextromethorphan + GS4071 DCN5MGT Dextromethorphan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ethinyl estradiol + GS4071 DCX7Z41 Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Ribavirin-TP DCJ80J0 Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Lefaxin DC2J4PP Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Diethylcarbamazine DCY8W7M Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Dactinomycin DCYKI38 Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + PMID28460551-Compound-2 DCKVLG2 PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Vinblastine DCP2Z2U Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + 10-hydroxycamptothecin DCAB1O2 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + IT-141 DCQ0DEO IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Metyrosine DCCRJ7I Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Terameprocol DCCF506 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Emetine DCTL21K Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Chlorzoxazone DC47NI5 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Pazopanib DC1JWE3 Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Fluspirilene DCNSVEE Fluspirilene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + BIO-300 DCDOYOX BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Niclosamide DCWU77P Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Trifluoperazine DCJTJOR Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Diazoxide DCZE1RE Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Imatinib DCOZVGV Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Pramipexole DCYR3BC Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Bortezomib DCL4LRX Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Methylene blue DCZMMHN Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Oxyphenbutazone DC8FVX8 Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Brincidofovir DC8TIXZ Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Estramustine DC509ZP Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Cerivastatin DCUMAW1 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Enoxacin DC62ZFQ Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Tetracycline DCDT8J0 Tetracycline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 32 DrugCom(s)

References

1 Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.