Details of the Drug Combinations

General Information of This Drug (ID: DMLVSYX)

Drug Name

Remimazolam DMLVSYX

Synonyms

CNS-7054; CNS-7056; CNS-7056B; CNS-7056X; GW-351564X; GW-418259X; GW-457837A; GW-502056X; ONO-2745; Short-acting sedatives, Therasci; GABA A agonist (anesthesia, sedation) CeNeS/Ono; Sedatives (short acting), CeNeS/Ono; Sedatives (short acting), PAION/Ono; Sedatives (short-acting), TheraSci; Short-acting sedatives, Therasci/GSK; Sedatives (short-acting), TheraSci/GSK

Indication

Disease Entry	ICD 11	Status	REF
Procedural sedation	JB0C.3	Approved	[1]
Anaesthesia	9A78.6	Phase 3	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

6 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Fentanyl + Remimazolam	DCPWP9J	Fentanyl	Gastrointestinal Endoscopy	[3]
Remimazolam + Esketamine	DCV6J8R	Esketamine	Drug Effect	[4]
Remimazolam + Remifentanil	DC7FJ8J	Remifentanil	Anesthesia	[5]
Fentanyl + Remimazolam	DCGT2EP	Fentanyl	General Anesthesia	[6]
Remimazolam + Esketamine	DCAB46G	Esketamine	Anesthesia	[7]
Fentanyl + Remimazolam	DC4G38Y	Fentanyl	General Anaesthesia	[8]
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⏷ Show the Full List of 6 DrugCom(s)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8442).
3	ClinicalTrials.gov (NCT05485064) Moderate Sedation Combined With Acupuncture Anesthesia in Gastroscopy and Colonoscopy on Screening Research
4	ClinicalTrials.gov (NCT05686863) Remiazolam Combined With Esketamine in Painless Bidirectional Endoscopy in Children
5	ClinicalTrials.gov (NCT04670471) Assessment of the Pharmacodynamic and Pharmacokinetic Interaction of Remimazolam and Remifentanil
6	ClinicalTrials.gov (NCT01937767) Remimazolam Phase II Cardiac Anesthesia Study
7	ClinicalTrials.gov (NCT05635955) Remimazolam Versus Propofol for Painless Abortion
8	ClinicalTrials.gov (NCT03669484) Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia