Details of the Drug Combinations

General Information of This Drug (ID: DMMQ8ZG)

Drug Name
Furosemide   DMMQ8ZG
Synonyms
Aisemide; Aldalix; Aldic; Aluzine; Anfuramaide; Aquarid; Aquasin; Arasemide; Beronald; Bioretic; Cetasix; Depix; Desal; Desdemin; Dirine; Disal; Discoid; Disemide; Diural; Diurapid; Diurin; Diurolasa; Diusemide; Diusil; Diuzol; Dranex; Dryptal; Durafurid; Edemid; Edenol; Eliur; Endural; Errolon; Eutensin; FUN; Farsix; Fluidrol; Fluss; Franyl; Frumex; Frumide; Frusedan; Frusema; Frusemid; Frusemide; Frusemin; Frusenex; Frusetic; Frusid; Fulsix; Fuluvamide; Fuluvamine; Fulvamide; Furanthril; Furanthryl; Furantral; Furantril; Furanturil; Furesis; Furetic; Furex; Furfan; Furix; Furmid; Furobeta; Furocot; Furodiurol; Furodrix; Furomen; Furomex; Furorese; Furosan; Furose; Furosedon; Furosemid; Furosemida; Furosemidu; Furosemidum; Furosemix; Furoside; Furosifar; Furosix; Furoter; Furovite; Fursemid; Fursemida; Fursemide; Fursol; Fusid; Golan; Hissuflux; Hydrex; Hydro; Hydroled; Impugan; Jenafusid; Katlex; Kofuzon; Kolkin; Kutrix; Lasemid; Lasex; Lasiletten; Lasilix; Lasix; Laxur; Lazix; Liside; Logirene; Lowpston; Lowpstron; Luscek; Macasirool; Marsemide; Mirfat; Mita; Moilarorin; Myrosemide; Nadis; Nelsix; Novosemide; Odemase; Odemex; Oedemex; Prefemin; Profemin; Promedes; Promide; Protargen; Puresis; Radisemide; Radonna; Radouna; Retep; Rosemide; Rosis; Rusyde; Salinex; Salix; Salurex; Salurid; Seguril; Selectofur; Sigasalur; Spirofur; Synephron; Transit; Trofurit; Uremide; Uresix; Urian; Uridon; Uritol; Urosemide; Vesix; Yidoli; Zafimida; FUROSEMIDE USP; Fu sid; Furosemide Monohydrochloride; Furosemide Monosodium Salt; Furosemidu [Polish]; Lasix Retard; Lasix Special; Less Diur; Polysquall A; Sal diureticum; F0182; F4381_SIGMA; LB 502; Aisemide (TN); Apo-Frusemide; Apo-Furosemide; Beronald (TN); Desdemin (TN); Discoid (TN); Diumide-K; Diural (TN); Diurapid (TN); Dryptal (TN); Durafurid (TN); Errolon (TN); Eutensin (TN); Frudix (TN); Frusetic (TN); Frusid (TN); Fulsix (TN); Fuluvamide (TN); Furesis (TN); Furix (TN); Furo-Basan; Furo-puren; Furomide M.D; Furosedon (TN); Furosemida [INN-Spanish]; Furosemide (mita); Furosemidum [INN-Latin]; Hoe-058A; Hydro-rapid; Impugan (TN); Katlex (TN); LB-502; Lasilix (TN); Lasix (TN); Lodix (TN); Lowpston (TN); Macasirool (TN); Mirfat (TN); Neo-renal; Nicorol (TN); Odemase (TN); Oedemex (TN); Profemin (TN); Rosemide (TN); Rusyde (TN); Salix (TN); Salix (brand of furosemide); Trofurit (TN); Urex (TN); Urex-M; Apo-Furosemide (TN); Furo-Puren (TN); Furomide M.D.; Furosemide [USAN:INN:JAN]; Hydro-rapid(TN); Lasix, Frusemide, Furosemide; Furosemide (JP15/USP/INN); Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure; Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure [German]; 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid; 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid; 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid; 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid; 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid; 4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
Indication
Disease Entry ICD 11 Status REF
Congestive heart failure BD10 Approved [1]
Edema MG29 Approved [2]
Renal hypoplasia N.A. Approved [2]
Therapeutic Class
Diuretics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

16 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
AKB-6548 + Furosemide DC5JKS7 AKB-6548 Drug Interaction Potentiation [3]
Aminophylline + Furosemide DCX3BJ6 Aminophylline Acute Kidney Injury [4]
Furosemide + Losartan DCBQLEV Losartan Essential Hypertension [5]
Furosemide + Torasemide DCFPPXI Torasemide Renal Impairment [6]
Furosemide + Mannitol DCQEDDL Mannitol Brain Tumors [7]
Furosemide + Spironolactone DCLDL9I Spironolactone AML [8]
Naproxcinod + Furosemide DC9ILIU Naproxcinod Renal Hemodynamics [9]
Probenecid + Furosemide DCLUTXO Probenecid Interaction [10]
Tolvaptan + Furosemide DC821OA Tolvaptan Pulmonary Arterial Hypertension [11]
Aminophylline + Furosemide DCCPM87 Aminophylline Acute Kidney Injury [12]
Chlorthalidone + Furosemide DCMNTO5 Chlorthalidone End Stage Renal Disease on Dialysis [13]
Furosemide + Amiloride DCGH818 Amiloride Hypertension Resistant to Conventional Therapy [14]
Furosemide + Bumetanide DCQ6FPL Bumetanide Heart Failure, Congestive [15]
Furosemide + Hydrochlorothiazide DC8VG3U Hydrochlorothiazide Heart Failure [16]
Furosemide + Dopamine DCWBFT1 Dopamine Heart Failure, Diastolic [17]
Labetalol + Furosemide DCFX5DT Labetalol Hypertension, Pregnancy-Induced [18]
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⏷ Show the Full List of 16 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4839).
2 Furosemide FDA Label
3 ClinicalTrials.gov (NCT03801759) Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide
4 ClinicalTrials.gov (NCT02983422) Effects of Aminophylline on Renal Function and Urine Volume of AKI Patient
5 ClinicalTrials.gov (NCT00151827) Olmesartan Medoxomil in Hypertension and Renal Impairment
6 ClinicalTrials.gov (NCT01558674) A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011)
7 ClinicalTrials.gov (NCT02712476) Brain Relaxation With Mannitol and Furosemide
8 ClinicalTrials.gov (NCT02575963) Lintuzumab-Ac225 in Older Acute Myeloid Leukemia (AML) Patients
9 ClinicalTrials.gov (NCT00909519) Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide
10 ClinicalTrials.gov (NCT05365451) Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters
11 ClinicalTrials.gov (NCT05569655) Efficacy and Safety Evaluation of Tolvaptan in the Treatment of Patients With RHF Caused by PAH
12 ClinicalTrials.gov (NCT05933642) Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults
13 ClinicalTrials.gov (NCT05915286) Diuretic Use in Hemodialysis Patients With Residual Renal Function
14 ClinicalTrials.gov (NCT02832973) Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension
15 ClinicalTrials.gov (NCT06218199) Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts
16 ClinicalTrials.gov (NCT03892148) Protocol of Diuretics Use in Congestive Therapy in Heart Failure
17 ClinicalTrials.gov (NCT01901809) Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction
18 ClinicalTrials.gov (NCT04343235) Postpartum Management of Gestational Hypertensive Disorders Using Furosemide