General Information of This Drug (ID: DMO381I)

Drug Name
Acamprosate   DMO381I
Synonyms
AOTA; Acamprosato; Acamprosatum; Acamprostate; Aotal; Campral; Calcium acetyl homotaurinate; Calcium acetylhomotaurinate; Calcium acetylhomotaurine; Sodium acetylhomotaurine; Acamprosate 6473; Acamprosate (Campral); Acamprosate (INN); Acamprosate [INN:BAN]; Acamprosato [INN-Spanish]; Acamprosatum [INN-Latin]; Aotal (TN); Campral (TN); N-Acetylhomotaurine; 3-(Acetylamino)propanesulphonic acid; 3-Acetamido-1-propanesulfonic acid; 3-acetamidopropane-1-sulfonic acid
Indication
Disease Entry ICD 11 Status REF
Alcohol dependence 6C40.2 Approved [1]
Therapeutic Class
Alcohol Deterrents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

161 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Meclofenamic acid DCVY9NE Meclofenamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Ribavirin-TP DCN7T6U Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Pentostatin DCW4ZKI Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Triiodothyronine DCXPNJH Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Clindamycin DCEB6FA Clindamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Acetazolamide DC28POI Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Paromomycin DCC0J6W Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Aliskiren DCU7CN1 Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Dantrolene DCNY6S3 Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Diethylcarbamazine DCBJ415 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Lumefantrine DCKTNWN Lumefantrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Triamterene DCCU3QG Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Dactinomycin DC45MA9 Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Terazosin DCZMZ1D Terazosin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Epinephrine DC4HRFQ Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + GYKI-52466 DCT69YD GYKI-52466 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + PMID28460551-Compound-2 DCD7PMK PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Tacrine DCM3LUU Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Trioxsalen DCIOJF0 Trioxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Methotrexate DC7V00K Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Miglustat DCSALEU Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Sivelestat DCFBMTL Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Anamorelin DCVFNNJ Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Pazopanib HCl DCCKFQO Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Ezetimibe DCQL0BC Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Testosterone DCAGHL3 Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Ramelteon DCVDLX4 Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Triapine DCNPE2Y Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Tranexamic acid DCBUZ9P Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Dronedarone DCZPC9Y Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Rifampin DC7R9XS Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + IT-141 DCXKRU0 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + BHV-0223 DCDK0ZH BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Metyrosine DCF10LB Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Testosterone cypionate DCJHVY7 Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Terameprocol DCV99L4 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + SCH 727965 DC8MXHM SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Amodiaquine DCW8K4E Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Ursodeoxycholic acid DCQ1BCU Ursodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Cinacalcet DCOIHQ9 Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Carglumic acid DC43UYP Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Docetaxel DCBRHYT Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + ETHISTERONE DCS09R3 ETHISTERONE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + LY03004 DC9X220 LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Methoxsalen DC6NEP0 Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Aminosalicylic acid DCPGS94 Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Galantamine DC9JARX Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Sulfinpyrazone DCLE7T8 Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Pazopanib DCY8GED Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Fibrates DC8H5QX Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + WAY-100635 DCIIN49 WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Armodafinil DCIBHOA Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Sitagliptin DCAVSLI Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Nizatidine DCVOBBB Nizatidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Zaleplon DCH2HWV Zaleplon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Mecamylamine DCF950E Mecamylamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + PHA-739358 DCWOS2Z PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Dichlorphenamide DCGEIXB Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Clopidogrel DCOA82L Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Diphenidol DCT5XNO Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Pentamidine DCYIC5P Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Tolazoline DC9360S Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Bosentan DC6W59P Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + PFK-158 DCURUR2 PFK-158 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Arfolitixorin DCKG57X Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Triflupromazine DCWFS3C Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + BIO-300 DCX9K3B BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Niclosamide DCZ7HIF Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + PF-02545920 DCVV5H5 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Norcisapride DCB03DI Norcisapride Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Lubiprostone DC9ICGV Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Tiagabine DCOZC1X Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Ibutilide DCA5V76 Ibutilide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Diazoxide DC3SFGD Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Fenoprofen DC8W6SG Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Tamoxifen DCPJU19 Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Entacapone DCKBJXF Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Idarubicin DCMHLF2 Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Acamprosate + BRL-15572 DCHWB76 BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Imatinib DCNVSCP Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Linagliptin DCO5AMJ Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Pramipexole DCFMHW6 Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Bortezomib DC57KL4 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Methylene blue DCTCYNA Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Mebendazole DC9417Y Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Acamprosate DCJRMFX Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Ethinyl estradiol DCJC2L5 Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Mesalazine DCJZEUU Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Topotecan DCQNIGF Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Clascoterone DCOILLV Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Cefmenoxime DCSUFZH Cefmenoxime Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Miconazole DCKQCM0 Miconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Trimethobenzamide DCF89Q5 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Maprotiline DCSEZZG Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Oxyphenbutazone DCYVR0G Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Teriflunomide DCE4TCO Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Eptifibatide DCBNG8Y Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Ethambutol DCEAC2N Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Leflunomide DCFVZE8 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Theophylline DCJIZCE Theophylline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Amiloride DCWIS3C Amiloride Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Bumetanide DCEQJC9 Bumetanide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Brincidofovir DC926TA Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Valproic Acid DCVN4PG Valproic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Desoxycorticosterone pivalate DCWGHFQ Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Chloroquine DCF9X8R Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Asenapine DCB16FS Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Naltrexone DCU31LM Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Loperamide DC2HS3G Loperamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Pomalidomide DCOUKGB Pomalidomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Spironolactone DCH80QT Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Maraviroc DCJ21ID Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Endoxifen DCCRBKT Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Hydralazine DCC09UG Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Cisatracurium DCY764T Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Mefloquine DCK9UEK Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Fosfomycin DCZHCJ7 Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Lacosamide DCTNDHJ Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Nitisinone DC7YMHN Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Sumatriptan DCSBLTM Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Olmesartan medoxomil DCX06P9 Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Auranofin DCZF35R Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Rufinamide DC153ZX Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + FORMESTANE DCOWL1W FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Vorinostat DCSP0Q9 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Estramustine DCP5GE9 Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Cerivastatin DC61LQE Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Metaxalone DC0DFBK Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Busulfan DCHFWPX Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Aciclovir DCVHPKT Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Acetohydroxamic Acid DCMDF1X Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + AS-1949490 DC2ICRK AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + GSK2194069 DCT62NR GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Azatadine DC35XCV Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Nitrosoglutathione DCOZ270 Nitrosoglutathione Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Cytarabine DCG0OMP Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Cilostazol DCR2339 Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + L-165041 DCBQ15Y L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aprepitant + Acamprosate DCQYMLN Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + Acamprosate DCWGS2Z Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cerivastatin + Acamprosate DC1MQT9 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorzoxazone + Acamprosate DCQPORK Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + Acamprosate DCQ4TMR Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + Acamprosate DCG00W8 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Acamprosate DC03ZGB Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Acamprosate DCDGQN0 Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Doxorubicin + Acamprosate DCZ4SK7 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Estramustine + Acamprosate DC9MG7S Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fenoprofen + Acamprosate DCS67Z8 Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fomepizole + Acamprosate DCEOWI4 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imatinib + Acamprosate DCTT768 Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Leflunomide + Acamprosate DC2QAK3 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Acamprosate DCG29GL Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metyrosine + Acamprosate DCDAKH2 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Niclosamide + Acamprosate DCHSGXC Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pepstatin + Acamprosate DC5F2OZ Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PFK-158 + Acamprosate DCDCVC7 PFK-158 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Quinine + Acamprosate DCI23SA Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tiagabine + Acamprosate DCMF3FE Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triiodothyronine + Acamprosate DCDJ6YQ Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + Acamprosate DCM78W5 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 161 DrugCom(s)
2 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Escitalopram + Acamprosate DCI7K4U Escitalopram Major Depressive Disorder [3]
Vortioxetine + Acamprosate DCPEEBC Vortioxetine Depressive Disorder, Major [4]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7106).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 ClinicalTrials.gov (NCT00452543) Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism
4 ClinicalTrials.gov (NCT04498897) Vortioxetine for Treatment of Depressive Mood and Alcohol Use