Details of the Drug Combinations

General Information of This Drug (ID: DMOJ0V6)

Drug Name

Metoprolol DMOJ0V6

Synonyms

Beatrolol; BelocDuriles; Betaloc; BetalocAstra; Betalok; Dutoprol; LOPRESSIDONE; Lopresor; Lopresoretic; Lopressor; Meijoprolol; Metohexal; Metoprololum; Metroprolol; Preblok; Presolol; Seloken; Seroken; Spesicor; Spesikor; Toprol; AstraZeneca Brand of Metaoprolol Tartrate; AstraZeneca Brand of Seloken; Beloc Duriles; Betaloc Astra; Leiras Brand of Metoprolol Succinate or Metoprolol Tartrate; Metoprolol succinate; Novartis Brand of Metprolol Tartrate; Seloken AstraZeneca Brand; CGP 2175; CGP2175; H 93 26; H 9326; Beloc-Duriles; Betaloc (TN); Betaloc-Astra; CGP-2175; Corvitol (TN); Dl-Metoprolol; H 93-26; Lopressor (TN); Metoprololum [INN-Latin]; Metrol (TN); Minax (TN); Neobloc (TN); Selo-Zok; Selokeen (TN); TOPROL-XL; Tartrate, Metoprolol; Metoprolol (USAN/INN); Metoprolol [USAN:INN:BAN]; Toprol-XL (TN); (RS)-Metoprolol; 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol; 1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol; 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol; 1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol; 1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol; 3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol

Indication

Disease Entry	ICD 11	Status	REF
Acute coronary syndrome	BA41	Approved	[1]
Angina pectoris	BA40	Approved	[1]
Cardiac arrest	MC82	Approved	[1]
Chronic heart failure	BD1Z	Approved	[1]
Hypertension	BA00-BA04	Approved	[2]
Malignant essential hypertension	BA00	Approved	[1]
Myocardial infarction	BA41-BA43	Approved	[1]
Obesity	5B81	Approved	[1]
Ventricular fibrillation	BC71.1	Approved	[1]
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⏷ Show the Full List of Indication(s)

Therapeutic Class

Antihypertensive Agents

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

4 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Metoprolol + Enoximone	DC7NVJH	Enoximone	Heart Failure, Congestive	[3]
Nebivolol + Metoprolol	DC5SYJY	Nebivolol	Hypertension	[4]
Nebivolol + Metoprolol	DCY5WX6	Nebivolol	High Blood Pressure	[5]
Carvedilol + Metoprolol	DCR5LXX	Carvedilol	Pulmonary Disease, Chronic Obstructive	[6]
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References

1	Metoprolol FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 553).
3	ClinicalTrials.gov (NCT00077948) Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure
4	ClinicalTrials.gov (NCT01041287) Effect of Nebivolol on Oxidative Stress and Endothelial Progenitor Cells
5	ClinicalTrials.gov (NCT01049009) The Effect of Nebivolol on Endothelial Dysfunction in African Americans With Hypertension
6	ClinicalTrials.gov (NCT03370835) Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD