Details of the Drug Combinations

General Information of This Drug (ID: DMPGUCF)

Drug Name

Dopamine DMPGUCF

Synonyms

Dopamin; Dopamina; Dopaminum; Dophamine; Hydroxytyramin; Hydroxytyramine; Intropin; LDP; Oxytyramine; Revimine; ASL 279; IP 498; Dopamina [INN-Spanish]; Dopamine (INN); Dopamine [INN:BAN]; Dopaminum [INN-Latin]; L-DOPAMINE; M-Hydroxytyramine hydrochloride; Medopa (TN); Intropin [*hydrochloride*]; KW-3-060; Beta-(3,4-Dihydroxyphenyl)ethylamine hydrochloride; Dopamine (USAN)(*hydrochloride*); A-(3,4-Dihydroxyphenyl)-b-aminoethane; Alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane; Pyrocatechol, 4-(2-aminoethyl)-(8CI); Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride; (3H)-Dopamine; 1,2-Benzenediol, 4-(2-aminoethyl)-(9CI); 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride; 1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium; 153C5321-5FEE-4B0B-8925-F388F0EEEBD1; 2-(3,4-dihydroxyphenyl)ethylamine; 2-benzenediol; 3,4-Dihydroxyphenethylamine hydrochloride; 3,4-Dihydroxyphenylethylamine; 3,4-dihydroxyphenethylamine; 3-Hydroxtyramine; 3-Hydroxytyramine; 3-Hydroxytyramine Hydrobromide; 3-Hydroxytyramine hydrochloride; 4-(2-Aminoethyl)-1; 4-(2-Aminoethyl)-1,2-benzenediol; 4-(2-Aminoethyl)-1,2-bezenediol; 4-(2-Aminoethyl)benzene-1,2-diol; 4-(2-Aminoethyl)catechol; 4-(2-Aminoethyl)pyrocatechol; 4-(2-Aminoethyl)pyrocatechol hydrochloride; 4-(2-aminoethyl)-pyrocatechol

Indication

Disease Entry	ICD 11	Status	REF
Acromegaly	5A60.0	Approved	[1]
Carcinoid syndrome	5B10	Approved	[1]
Parkinson disease	8A00.0	Approved	[2]
Parkinsonian disorder	N.A.	Approved	[1]
Postencephalitic Parkinson disease	N.A.	Approved	[1]
Hypotension	BA20-BA21	Phase 1	[2]
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Therapeutic Class

Cardiotonic Agents

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

60 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Arfolitixorin + Dopamine	DCJ3336	Arfolitixorin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Dopamine	DCEVXCK	Armodafinil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
BIO-300 + Dopamine	DCK8TPZ	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Bortezomib + Dopamine	DCN14GT	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Brincidofovir + Dopamine	DC2CYYP	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cerivastatin + Dopamine	DCSQAY2	Cerivastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Chlorzoxazone + Dopamine	DCGEMO3	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Crotamiton + Dopamine	DCIQYMH	Crotamiton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Triiodothyronine	DC0Z90N	Triiodothyronine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Gefitinib	DCCDRIQ	Gefitinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Kanamycin	DCK7BIR	Kanamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Vinblastine	DCF1LY8	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Triapine	DCWYF3L	Triapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Everolimus	DCBBMX3	Everolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + IT-141	DCAOKRL	IT-141	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Metyrosine	DCVEQ08	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Docetaxel	DC7FI8H	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Phensuximide	DCKDKDZ	Phensuximide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Fluspirilene	DC8BTU7	Fluspirilene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + PHA-739358	DCIA3K4	PHA-739358	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Clopidogrel	DCPCBUW	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Diazoxide	DCK19MW	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Allopurinol	DCI8WAU	Allopurinol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Pramipexole	DCS4F0L	Pramipexole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Methylene blue	DCN9G8M	Methylene blue	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Topotecan	DCGRSN4	Topotecan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Clascoterone	DCYVG6D	Clascoterone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Trimethobenzamide	DC3WAPW	Trimethobenzamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Desoxycorticosterone pivalate	DC2RHEK	Desoxycorticosterone pivalate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Naltrexone	DC0NTD6	Naltrexone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Endoxifen	DCFYYV2	Endoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Mycophenolic acid	DCBIBI4	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Hydralazine	DCKJ102	Hydralazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Mefloquine	DCJF0IP	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + PMID28870136-Compound-43	DCZOLWY	PMID28870136-Compound-43	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Vorinostat	DCUYYUK	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + ML323	DCVV3ZM	ML323	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Nitrosoglutathione	DCKHO60	Nitrosoglutathione	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Doxorubicin + Dopamine	DCU1XD0	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Emetine + Dopamine	DCYBWSF	Emetine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Dopamine	DCE14KI	Epinephrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fomepizole + Dopamine	DCZ39FG	Fomepizole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Hyodeoxycholic acid + Dopamine	DCYSXDL	Hyodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Imatinib + Dopamine	DC1UVE8	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
K-134 + Dopamine	DCU7KTV	K-134	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lumefantrine + Dopamine	DCV6QHL	Lumefantrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Maprotiline + Dopamine	DCYMDV7	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Miglustat + Dopamine	DCK5KA9	Miglustat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Nizatidine + Dopamine	DC3G73E	Nizatidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Norcisapride + Dopamine	DCA31N8	Norcisapride	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Oxyphenbutazone + Dopamine	DCOSKT2	Oxyphenbutazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Paromomycin + Dopamine	DCWQ7WE	Paromomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PF-02545920 + Dopamine	DC62V8O	PF-02545920	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pizotyline + Dopamine	DC3K9EY	Pizotyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PMID28460551-Compound-2 + Dopamine	DCUBIUT	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pyrazinamide + Dopamine	DCASF80	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Repaglinide + Dopamine	DCZ2H63	Repaglinide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ribavirin-TP + Dopamine	DCW70PK	Ribavirin-TP	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Triamterene + Dopamine	DCON7IB	Triamterene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ursodeoxycholic acid + Dopamine	DCDUMPE	Ursodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
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⏷ Show the Full List of 60 DrugCom(s)

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Hydrocortisone + Dopamine	DCZA04Q	Hydrocortisone	Infant, Newborn	[4]
Dopamine + Alprostadil	DC15JJC	Alprostadil	Children AKI Patients	[5]
Furosemide + Dopamine	DCWBFT1	Furosemide	Heart Failure, Diastolic	[6]
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References

1	Dopamine FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 940).
3	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4	ClinicalTrials.gov (NCT00874393) Early Blood Pressure Management in Extremely Premature Infants
5	ClinicalTrials.gov (NCT03892447) The Comparative Effectiveness of Alprostadil,Sodium Ferulate and Dopamine in Pediatric Acute Kidney Injury
6	ClinicalTrials.gov (NCT01901809) Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction