General Information of This Drug (ID: DMPWB7T)

Drug Name
Maprotiline   DMPWB7T
Synonyms
Deprilept; Dibencycladine; Maprotilin; Maprotilina; Maprotilinum; Maprotylina; Maprotylina [Polish]; TBB066626; BA-34276; Deprilept (TN); Ludiomil (TN); Maprotilina [INN-Spanish]; Maprotiline (USAN); Maprotilinum [INN-Latin]; Psymion (TN); Ba-34,276; Maprotiline [USAN:BAN:INN]; N-Methyl-9,10-ethanoanthracene-9(10H)-propanamine; N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine; 3-(9,10-Dihydro-9,10-ethanoanthracen-9-yl)propylmethylamine; 3-(9,10-ethanoanthracen-9(10H)-yl)-N-methylpropan-1-amine
Indication
Disease Entry ICD 11 Status REF
Depression 6A70-6A7Z Approved [1]
Major depressive disorder 6A70.3 Approved [2]
Mixed anxiety and depressive disorder N.A. Investigative [1]
Therapeutic Class
Antidepressants
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

248 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Maprotiline DCSEZZG Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetohydroxamic Acid + Maprotiline DCKW4U2 Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acitretin + Maprotiline DCTZJXK Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Aliskiren + Maprotiline DCRAE28 Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Allopurinol + Maprotiline DCUU5QF Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Aminosalicylic acid + Maprotiline DC1QRQG Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Amodiaquine + Maprotiline DCXCZAW Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Armodafinil + Maprotiline DCMUNP3 Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Artemisinin + Maprotiline DCOLCR1 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
AS-1949490 + Maprotiline DCMV2ZN AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Asenapine + Maprotiline DCH63UP Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atovaquone + Maprotiline DCT5NWS Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Maprotiline DCADJ81 Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Baclofen + Maprotiline DC9XY89 Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bepridil + Maprotiline DCAYVHA Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bortezomib + Maprotiline DCNTWA5 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bosentan + Maprotiline DC2VBMA Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BRL-15572 + Maprotiline DCMMY8T BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Buspirone + Maprotiline DCBPD5V Buspirone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Busulfan + Maprotiline DCISWG2 Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chlormezanone + Maprotiline DCKMQWK Chlormezanone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chloroquine + Maprotiline DCIPKJG Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chlorphenesin + Maprotiline DCFQ9T4 Chlorphenesin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cilastatin + Maprotiline DCNFGY1 Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cinacalcet + Maprotiline DC4RFEE Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ciprofibrate + Maprotiline DCHF3NA Ciprofibrate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cisatracurium + Maprotiline DCU3GGP Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Citalopram + Maprotiline DCUTVVN Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clascoterone + Maprotiline DC8VLN3 Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clopidogrel + Maprotiline DCD4MHS Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Crotamiton + Maprotiline DC09Q7E Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dactinomycin + Maprotiline DCHOL5K Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Dantrolene + Maprotiline DC8QQE4 Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Darunavir + Maprotiline DCSMV6O Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dexmedetomidine + Maprotiline DCAZENE Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diazoxide + Maprotiline DCURFW5 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dichlorphenamide + Maprotiline DCQ5524 Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diethylcarbamazine + Maprotiline DCMBQZL Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diphenidol + Maprotiline DCUJGQ2 Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Docetaxel + Maprotiline DCLX1SQ Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Doxapram + Maprotiline DC8OIJ9 Doxapram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Doxorubicin + Maprotiline DCIV7P1 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Efavirenz + Maprotiline DCFLRS1 Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enalaprilat + Maprotiline DC0L4XA Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Endoxifen + Maprotiline DCT3VDJ Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Entacapone + Maprotiline DCGE6R2 Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Estramustine + Maprotiline DC6OFX5 Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Etomidate + Maprotiline DC8JHYX Etomidate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Etonogestrel + Maprotiline DCMYD2W Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fenoprofen + Maprotiline DCODARM Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fluspirilene + Maprotiline DCITPHK Fluspirilene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Furazolidone + Maprotiline DC13ZMB Furazolidone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Gefitinib + Maprotiline DCBMBAR Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ginsenoside Rb1 + Maprotiline DCZFZ2Y Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hydralazine + Maprotiline DC1LHRE Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hydroxychloroquine + Maprotiline DCIH97K Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hyodeoxycholic acid + Maprotiline DCP9CZ9 Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ibutilide + Maprotiline DC4K716 Ibutilide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Idarubicin + Maprotiline DCZEW61 Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Imipramine + Maprotiline DCXPL1Z Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Itraconazole + Maprotiline DCO0S4U Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
L-165041 + Maprotiline DCDHQOX L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lacosamide + Maprotiline DCKHU2B Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lefaxin + Maprotiline DCMJ8VT Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Leflunomide + Maprotiline DCQ8W38 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Maprotiline DCDKZGS Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Linagliptin + Maprotiline DCX058R Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Loperamide + Maprotiline DC75YO1 Loperamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lubiprostone + Maprotiline DCT60Q0 Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lumefantrine + Maprotiline DCVJ5AU Lumefantrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
LY03004 + Maprotiline DC6J1X7 LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Aprepitant DCFCJOV Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Meclofenamic acid DC8WJKK Meclofenamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Ribavirin-TP DCZ4NK3 Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Sertraline DCE7YET Sertraline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Pentostatin DC3XHE0 Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Mebutamate DC259TZ Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Picoplatin DCH5CYU Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Primidone DC3X2XA Primidone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Triiodothyronine DCRL766 Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Gefitinib DCG0TCL Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Clindamycin DC4LIW1 Clindamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Acetazolamide DCLUUSQ Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Aliskiren DCF8KQL Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Diethylcarbamazine DCT8N33 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Kanamycin DCS14AY Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Imipramine DCOLW01 Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Tindamax DC9YEC6 Tindamax Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Chlorphenesin DC5CAF2 Chlorphenesin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Panobinostat DC6KWAA Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Maprotiline + Dihydroergotamine DCLP5ZB Dihydroergotamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Miglustat DCPQT5F Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Repaglinide DCQENSX Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Mephenytoin DCLKD8N Mephenytoin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Anamorelin DCAFIOJ Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Pazopanib HCl DC3YDKZ Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Fomepizole DC34JCY Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Ezetimibe DCTP6NJ Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Testosterone DCWPF9C Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Triapine DCN2KF1 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Everolimus DCJ13TS Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + 10-hydroxycamptothecin DCQBIPI 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Dronedarone DCPKERF Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Rifampin DCCKV7V Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + IT-141 DCC2DLJ IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Methylergonovine DCU442B Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Isosorbide dinitrate DCEHBCM Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + BHV-0223 DC634JK BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Metyrosine DCKY8B4 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Efavirenz DC1BK5E Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Flavonoid derivative 1 DC5056P Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Emetine DCHAU8F Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Ursodeoxycholic acid DCL3V18 Ursodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Chlorzoxazone DCPB7XM Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + K-134 DCAI6FI K-134 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Metformin DC9DD9A Metformin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Cilastatin DCMEBJX Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Galantamine DCSV26G Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Daidzin DCAFEOB Daidzin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + VR-776 DCZ0BR3 VR-776 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Zaleplon DCPD5JV Zaleplon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Naringenin DCCS2DO Naringenin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Clopidogrel DCWVRAF Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Diphenidol DC6Z4KN Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Tolazoline DCCWT6P Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + PFK-158 DCX3NF0 PFK-158 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Sulfapyridine DCA9075 Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Tolvaptan DCY0EP2 Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + BIO-300 DCDUDJ7 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Niclosamide DCCRIZA Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Eflornithine DC06UG7 Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + PF-02545920 DCW9YHA PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Lubiprostone DCB73OG Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Isoproterenol DC0OOCT Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Tiagabine DC7DMO0 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Oseltamivir DCNSBX0 Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Ibutilide DC7J5W9 Ibutilide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + GINKGOLIDE A DCWNIKE GINKGOLIDE A Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Allopurinol DCYKVHH Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Benserazide DC5XNC2 Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Pargyline DCX2PFU Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Idarubicin DCS1OMC Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Methocarbamol DC37E1C Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + BRL-15572 DCNO8XF BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Probenecid DCP7R65 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Atenolol DC13ILI Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Methylene blue DCLUNCT Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Tropisetron DCXGB6Q Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Mebendazole DCNZ2H5 Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Ethinyl estradiol DCEW30V Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Mesalazine DCQCT60 Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Olanzapine DCDTCH6 Olanzapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Dopamine DCYMDV7 Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Trimethobenzamide DCKMEE0 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Oxyphenbutazone DCB8ZJS Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Eptifibatide DCYNA97 Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Ethambutol DC80OY6 Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Novobiocin DCCQBRX Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Theophylline DCTZCDU Theophylline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Chlorambucil DCTKHG9 Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Amiloride DCO4GBB Amiloride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Brincidofovir DCXP0HQ Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Amantadine DCLBM65 Amantadine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Sorafenib DCF52ID Sorafenib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Desoxycorticosterone pivalate DC86HGZ Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Asenapine DCQLN5M Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Spironolactone DC8HXAK Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Chlormezanone DC8V2ZP Chlormezanone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Endoxifen DCV0OOH Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Mycophenolic acid DCDIOMA Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Cisatracurium DCNXJMU Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Pizotyline DCEFZR0 Pizotyline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Iloprost DCZ3EBF Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Zileuton DC3PHE0 Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Nitisinone DCMURHS Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Testolactone DC1DDJB Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Sumatriptan DCLG2XC Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Olmesartan medoxomil DCXD21V Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Auranofin DC190SR Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + PMID28870136-Compound-43 DCX833M PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + FORMESTANE DC1GU3Q FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Vorinostat DCMJ3QE Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Cevimeline DC6MZ9X Cevimeline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Metaxalone DCVVGHR Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Aciclovir DCB22DG Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + AS-1949490 DC3GP20 AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + GSK2194069 DCVA66L GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Cytarabine DCFFLKM Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + L-165041 DCNU1DG L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maraviroc + Maprotiline DCXPFUL Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mecamylamine + Maprotiline DC1LB8Q Mecamylamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Meclofenamic acid + Maprotiline DCQIM2L Meclofenamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Maprotiline DCP1GBQ Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mesalazine + Maprotiline DCJSI6H Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metaxalone + Maprotiline DCXAXXS Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metformin + Maprotiline DCXO3F2 Metformin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Maprotiline DCHYSRJ Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methylene blue + Maprotiline DCA85ME Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methylergonovine + Maprotiline DCODE5S Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Maprotiline DCZRIJ4 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
ML323 + Maprotiline DCZJUY5 ML323 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Moricizine + Maprotiline DCEP2JB Moricizine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Niclosamide + Maprotiline DCZAXD5 Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Nitrosoglutathione + Maprotiline DCGCB3Y Nitrosoglutathione Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Nizatidine + Maprotiline DC1CS2P Nizatidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Norcisapride + Maprotiline DCK6L4O Norcisapride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Olanzapine + Maprotiline DC43Q65 Olanzapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Olmesartan medoxomil + Maprotiline DCTCF0L Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oxandrolone + Maprotiline DCNLVL2 Oxandrolone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oxyphenbutazone + Maprotiline DCRKAR2 Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pamidronate + Maprotiline DCY8H77 Pamidronate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pazopanib + Maprotiline DC9QF8D Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pazopanib HCl + Maprotiline DCJG41A Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pentamidine + Maprotiline DCYKEC8 Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pepstatin + Maprotiline DCSKEH3 Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PF-02545920 + Maprotiline DCDBW01 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PHA-739358 + Maprotiline DCNO35I PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Phensuximide + Maprotiline DC2VZDN Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pramipexole + Maprotiline DCYO3SW Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Procarbazine + Maprotiline DCTNH7W Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Quinine + Maprotiline DC1CJA0 Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ramelteon + Maprotiline DC16S4D Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Repaglinide + Maprotiline DCAY5VC Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Rifampin + Maprotiline DCZFXMM Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
SCH 727965 + Maprotiline DC3F6HG SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Silver sulfadiazine + Maprotiline DC7GFEM Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sitagliptin + Maprotiline DC56OQJ Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sivelestat + Maprotiline DCSWTV2 Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sulfinpyrazone + Maprotiline DCDQOX1 Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sumatriptan + Maprotiline DCUFSPK Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tamoxifen + Maprotiline DCZ1S7H Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Terameprocol + Maprotiline DCHYVGH Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Terazosin + Maprotiline DCOSHP0 Terazosin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Testolactone + Maprotiline DC2N1DE Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Testosterone cypionate + Maprotiline DCFYH9X Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Theophylline + Maprotiline DCGFRP9 Theophylline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tindamax + Maprotiline DCNT8O8 Tindamax Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tolazoline + Maprotiline DCOSQ8M Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Topotecan + Maprotiline DCV5BZ5 Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Triamterene + Maprotiline DCYCKPA Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trifluoperazine + Maprotiline DCWNO7Z Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triflupromazine + Maprotiline DCSYZZZ Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Maprotiline DCDT7WY Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Valproic Acid + Maprotiline DCBC549 Valproic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + Maprotiline DCQ5T34 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
VR-776 + Maprotiline DC1IC2W VR-776 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
WAY-100635 + Maprotiline DCT5QUE WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Zileuton + Maprotiline DCD22AN Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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References

1 Maprotiline FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.