General Information of This Drug (ID: DMSIWD0)

Drug Name
Hyodeoxycholic acid   DMSIWD0
Synonyms
A-Dihydroxy-5; A-cholan-24-oic acid; DGABKXLVXPYZII-SIBKNCMHSA-N; HYODEOXYCHOLIC ACID; Hyodeoxycholate; Hyodeoxycholic acid (HDCA); Hyodesoxycholic acid; Hyodesoxycholsaeure; Iodeoxycholic acid; alpha-Hyodeoxycholic acid; 3alpha,6alpha-Dihydroxy-5beta-cholan-24-oic acid; 3alpha,6alpha-Dihydroxy-5beta-cholanic acid; 3alpha,6alpha-Dihydroxy-5beta-cholanoic acid; 6alpha-Hydroxylithocholate; 7-Deoxyhyocholic acid; 7A33Y6EHYK; 83-49-8; CHEBI:52023; HDCA; MFCD00003681; NSC 60672; UNII-7A33Y6EHYK
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

128 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Hyodeoxycholic acid DC5VCWP 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Acarbose + Hyodeoxycholic acid DCSC8RI Acarbose Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Amodiaquine + Hyodeoxycholic acid DCV9LUY Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Atovaquone + Hyodeoxycholic acid DCFRXTL Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Baclofen + Hyodeoxycholic acid DCQSYEY Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Bepridil + Hyodeoxycholic acid DC3E4PN Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
BHV-0223 + Hyodeoxycholic acid DC7DI0F BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Bortezomib + Hyodeoxycholic acid DCOHDN2 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Bosentan + Hyodeoxycholic acid DC1X21S Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Brincidofovir + Hyodeoxycholic acid DCJFQ6G Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Cerivastatin + Hyodeoxycholic acid DCF55Z3 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Chloroquine + Hyodeoxycholic acid DC71058 Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Cilastatin + Hyodeoxycholic acid DCI9UNE Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Citalopram + Hyodeoxycholic acid DC447YX Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Clindamycin + Hyodeoxycholic acid DC66LBL Clindamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Clopidogrel + Hyodeoxycholic acid DCCQBLA Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Crotamiton + Hyodeoxycholic acid DCIY7IA Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Dactinomycin + Hyodeoxycholic acid DCM3VUC Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Hyodeoxycholic acid DCJHCIH Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Dichlorphenamide + Hyodeoxycholic acid DCPQ3T0 Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Dronedarone + Hyodeoxycholic acid DCKI5LI Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Endoxifen + Hyodeoxycholic acid DC4MKSO Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Entacapone + Hyodeoxycholic acid DCCTWCS Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Ethinyl estradiol + Hyodeoxycholic acid DCEBT2R Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Etonogestrel + Hyodeoxycholic acid DC14QP1 Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Fenoprofen + Hyodeoxycholic acid DCKE3MI Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
FORMESTANE + Hyodeoxycholic acid DC5XG3S FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Fosfomycin + Hyodeoxycholic acid DCB5VTY Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Gefitinib + Hyodeoxycholic acid DCW96LK Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hydroxychloroquine + Hyodeoxycholic acid DCWABGP Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Mebutamate DCVK1YP Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Picoplatin DCV2RZ8 Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Triiodothyronine DCOSN81 Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Acetazolamide DCDG8FQ Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Aliskiren DC2D9FM Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Diethylcarbamazine DCGSFXQ Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Kanamycin DCBK2AS Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Furazolidone DCV9OTH Furazolidone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + PMID28460551-Compound-2 DCTE6UW PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Miglustat DCT0OAJ Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Anamorelin DC7MKHI Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Fomepizole DCM0MV6 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Acitretin DC2SPO3 Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + 10-hydroxycamptothecin DCQYFOB 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Rifampin DC2UMU6 Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Isosorbide dinitrate DC6VK0I Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Guanfacine DCHGMOM Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + SCH 727965 DCEEE09 SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Emetine DC9UMA8 Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Cinacalcet DCGDEM0 Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Doxapram DCYTD3A Doxapram Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Galantamine DCFEKK5 Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Phensuximide DCU3Z19 Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Fibrates DCMNUBA Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + VR-776 DCITPZK VR-776 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Ciprofibrate DCV39PE Ciprofibrate Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Diphenidol DCV7GU3 Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Pentamidine DCQ763B Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Triflupromazine DCCHQ3G Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + BIO-300 DC2ON39 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Trifluoperazine DCMH0Q8 Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Diazoxide DCJZ273 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Allopurinol DC36KHM Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Idarubicin DC50A4Y Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Probenecid DCLD3HX Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Abacavir DC0XE4W Abacavir Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Darunavir DC1MSSQ Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Methylene blue DC3VDYC Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Artemisinin DC0ZFNB Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Dopamine DCYSXDL Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Trimethobenzamide DC71UEV Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Maprotiline DCP9CZ9 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Oxyphenbutazone DCH6NWP Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Ethambutol DC47IKU Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Theophylline DC2DKXU Theophylline Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Chlorambucil DCQGKCC Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Amiloride DCIRC9D Amiloride Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Brincidofovir DCXDSO9 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Naltrexone DC33KYA Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Pomalidomide DCSSFSS Pomalidomide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Spironolactone DCIGP8X Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Mycophenolic acid DC4MKJ4 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Cisatracurium DCGITVF Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Mefloquine DCNPRZP Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Lacosamide DC5Y247 Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Iloprost DCE4EWN Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Nabilone DCYSIUE Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Nitisinone DCW1BZH Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Silver sulfadiazine DC4VPRI Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Testolactone DCZSZ9J Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Vorinostat DCJ5QS6 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Estramustine DCKAP3O Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Metaxalone DC63F8G Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Aciclovir DC0OHIN Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Enoxacin DCF5QJD Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Azatadine DC3BA4N Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Hyodeoxycholic acid + Ruxolitinib DC763E5 Ruxolitinib Hodgkin lymphoma (Cell Line: L-1236) [2]
Ibutilide + Hyodeoxycholic acid DC8RG1C Ibutilide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Imipramine + Hyodeoxycholic acid DCSSFEX Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Isoproterenol + Hyodeoxycholic acid DCHOEOI Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Levamisole + Hyodeoxycholic acid DCENKJ9 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Maraviroc + Hyodeoxycholic acid DCQYABG Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Mebendazole + Hyodeoxycholic acid DCX3GDG Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Mecamylamine + Hyodeoxycholic acid DC3X7HN Mecamylamine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Methocarbamol + Hyodeoxycholic acid DC1228E Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
ML323 + Hyodeoxycholic acid DCFFFGJ ML323 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Mycophenolic acid + Hyodeoxycholic acid DCCYF3Z Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Naringenin + Hyodeoxycholic acid DCVN0QU Naringenin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Palonosetron + Hyodeoxycholic acid DCKI246 Palonosetron Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Pazopanib + Hyodeoxycholic acid DCZYOJZ Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
PFK-158 + Hyodeoxycholic acid DCTARK5 PFK-158 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
PHA-739358 + Hyodeoxycholic acid DCTMJ8P PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Phenprocoumon + Hyodeoxycholic acid DCBS1I6 Phenprocoumon Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Procarbazine + Hyodeoxycholic acid DC2DZCS Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Quinine + Hyodeoxycholic acid DCX22MG Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Ramelteon + Hyodeoxycholic acid DCTE0WY Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Repaglinide + Hyodeoxycholic acid DCY5EOI Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Sertraline + Hyodeoxycholic acid DCMUFWX Sertraline Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Sitagliptin + Hyodeoxycholic acid DC1T5HZ Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Sumatriptan + Hyodeoxycholic acid DCFRQVI Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Tacrine + Hyodeoxycholic acid DCRGW5Q Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Teriflunomide + Hyodeoxycholic acid DC536OD Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Testosterone cypionate + Hyodeoxycholic acid DCUE5FW Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Tiagabine + Hyodeoxycholic acid DCA139K Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Tolazoline + Hyodeoxycholic acid DCIOUNK Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Topotecan + Hyodeoxycholic acid DCCIXOU Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triapine + Hyodeoxycholic acid DCO2WCL Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Valproic Acid + Hyodeoxycholic acid DC6L8XX Valproic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
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⏷ Show the Full List of 128 DrugCom(s)

References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
2 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.