General Information of This Drug (ID: DMUDJZM)

Drug Name
Dextromethorphan   DMUDJZM
Synonyms
Albutussin; Canfodion; Cosylan; Demorphine; Destrometerfano; Dextromethorfan; Dextromethorphane; Dextromethorphanum; Dextrometorfano; Dextrometorphan; Dextromorphan; Dexyromethorphan; Dormetan; Levomethorphan; Levomethorphane; Levomethorphanum; Levometorfano; Methorphan; RACEMETHORPHAN; Trocal; Balminil DM; Balminil DM Children; Benylin Adult Formula Cough Suppressant; Benylin DM for Children; Benylin Pediatric Cough Suppressant; Delsym Cough Formula; Demorphan hydrobromide; Destrometerfano [DCIT]; Dextromethorfan [Czech]; Dextromethorphan Bromhydrate; Hold DM; Koffex DM; Novahistex DM; Novahistine DM; Pertussin DM Extra Strength; Robitussin Maximum Strength Cough Suppressant; Robitussin Pediatric; Robitussin Pediatric Cough Suppressant; Triaminic DM Long Lasting for Children; BA 2666; Benylin DM 12 Hour; Benylin DM for Children 12 Hour; Sucrets 4 Hour Cough Suppressant; Vicks 44 Cough Relief; Calmylin #1; Cough-X; Creo-Terpin; D-Methorphan; Delta-Methorphan; Dextromethorphan (USP); Dextromethorphane [INN-French]; Dextromethorphanum [INN-Latin]; Dextrometorfano [INN-Spanish]; Diabe-Tuss DM Syrup; Hihustan M.; L-Methorphan; Levomethorphane [INN-French]; Levomethorphanum [INN-Latin]; Levometorfano [INN-Spanish]; Neurodex (TN); Pertussin CS Children's Strength; Romilar (TN); Dextromethorphan [USP:INN:BAN]; Levomethorphan [BAN:DCF:INN]; Levomethorphan [INN:BAN:DCF]; Morphinan, 3-methoxy-17-methyl-, (9-alpha,13-alpha,14-alpha)-(9CI); Cis-1,3,4,9,10,10a-Hexahydro-6-methoxy-11-methyl-2H-10,4alpha-iminoethanophenanthren; (+)-3-Methoxy-17-methylmorphinan; (-)-3-Methoxy-N-methylmorphinan; (9alpha,13alpha,14alpha)-17-methyl-3-(methyloxy)morphinan; 3-Methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan; 3-Methoxy-17-methylmorphinan; 3-Methoxy-N-methylmorphinon; 9alpha,13alpha,14alpha-Morphinan, 3-methoxy-17-methyl-(8CI)
Indication
Disease Entry ICD 11 Status REF
Allergic rhinitis CA08.0 Approved [1]
Common cold CA00 Approved [1]
Cough MD12 Approved [2]
Fever MG26 Approved [1]
Headache 8A80-8A84 Approved [1]
Rhinitis FA20 Approved [1]
Vasomotor/allergic rhinitis CA08 Approved [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Analgesics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

30 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Brincidofovir + Dextromethorphan DCLO710 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chlorzoxazone + Dextromethorphan DCCDAHZ Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dantrolene + Dextromethorphan DCD82PM Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Ribavirin-TP DC8UQB1 Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Diethylcarbamazine DC5P8PO Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Dactinomycin DCVGSYN Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Tindamax DCZMEHT Tindamax Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + PMID28460551-Compound-2 DC0H5KQ PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Methotrexate DCFKQI0 Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Vinblastine DCNJX3W Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + IT-141 DCH7RUJ IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Metyrosine DCG4YU6 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Terameprocol DCH0ZBN Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Emetine DC6BMEV Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Docetaxel DCJDP3D Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + GS4071 DCN5MGT GS4071 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Niclosamide DC0S5IL Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Tiagabine DCS1UBI Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Diazoxide DC1Z9XG Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Imatinib DCQVXNT Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Atenolol DCH17DU Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Leflunomide DCABJED Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Pinacidil DC9ZPX4 Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Brincidofovir DCKRMUE Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Nabilone DCITTQ2 Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Estramustine DCFZ7VK Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Cerivastatin DCJT0TU Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Enoxacin DCT5ICD Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Cytarabine DCF3GYJ Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
GSK2194069 + Dextromethorphan DC31Y91 GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 30 DrugCom(s)
2 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Isavuconazole + Dextromethorphan DCRO0BE Isavuconazole Pharmacokinetics of Isavuconazole [4]
Quinidine + Dextromethorphan DCVR90N Quinidine Diabetic neuropathy [5]
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References

1 Dextromethorphan FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6953).
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT01651325) Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects
5 Dextromethorphan/quinidine: AVP 923, dextromethorphan/cytochrome P450-2D6 inhibitor, quinidine/dextromethorphan. Drugs R D. 2005;6(3):174-7.