Details of the Drug Combinations

General Information of This Drug (ID: DMWX5CO)

Drug Name

Nicotine DMWX5CO

Synonyms

Habitrol; Micotine; NCT; NICOTINE AND SALTS; Nicoderm Patch; Nicotina [Italian]; Nicotine Patch; Nicotine [USAN]; Nicotine replacement patch; Nicotine solution; Nictoine patch; Nikotin [German]; Nikotyna [Polish]; Transdermal Nicotine; Nicotine [UN1654] [Poison]; ENT 3,424; Habitrol (TN); Nicorette (TN); Nicotine (USP); Nicotine (compounds related to); Nicotine [BSI:ISO]; L(-)-nicotine; Beta-Pyridyl-alpha-N-methyl pyrrolidine; (-)-Nicotine solution; (2S) 3-(1-Methyl-pyrrolidin-2-yl)-pyridine; (S)-(-)-NICOTINE, 3-[(2S)-1-METHYL-2-PYRROLIDINYL] PYRIDINE; (S)-(-)-Nicotine; (S)-3-(1-methylpyrrolidin-2-yl)pyridine; (S)-3-(N-methylpyrrolidin-2-yl)pyridine; (S)-Nicotine; 3-(2-(N-methylpyrrolidinyl))pyridine; 3-(N-Methylpyrollidino)pyridine; 3-(N-Methylpyrrolidino)pyridine; 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine

Indication

Disease Entry	ICD 11	Status	REF
Lung cancer	2C25.0	Approved	[1]
Nicotine dependence	6C4A.2	Approved	[2]
Pellagra	N.A.	Approved	[1]
Tobacco dependence	6C4A.2	Clinical trial	[3]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

9 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Bupropion + Nicotine	DC45HM2	Bupropion	Cigarette Smoking	[4]
Ethanol + Nicotine	DCP8Z0X	Ethanol	Alcohol Consumption	[5]
Menthol + Nicotine	DCQBPUF	Menthol	Nicotine Dependence	[6]
Nicotine + Exenatide	DC453R7	Exenatide	Smoking Cessation	[7]
Topiramate + Nicotine	DCI1OB2	Topiramate	Tobacco Dependence	[8]
Varenicline + Nicotine	DCLVMFC	Varenicline	Nicotine Dependence	[9]
Nicotine + Nicotine	DCGBFZG	Nicotine	Nicotine	[10]
Nicotine + Exenatide	DCBLAW4	Exenatide	Smoking Cessation	[11]
Varenicline + Nicotine	DC65DT3	Varenicline	Smoking Cessation	[12]
------------------------------------------------------------------------------------


⏷ Show the Full List of 9 DrugCom(s)

References

1	Nicotine FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2585).
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	ClinicalTrials.gov (NCT01560507) Tailored Smoking Cessation Treatment for LIVE FOR LIFE Participants
5	ClinicalTrials.gov (NCT00616746) Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans
6	ClinicalTrials.gov (NCT02102100) The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users
7	ClinicalTrials.gov (NCT02975297) Exenatide Once Weekly for Smoking Cessation
8	ClinicalTrials.gov (NCT00755716) Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study
9	ClinicalTrials.gov (NCT01406223) Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation
10	ClinicalTrials.gov (NCT04038515) Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes
11	ClinicalTrials.gov (NCT05610800) Exenatide for Smoking Cessation and Prevention of Weight Gain
12	ClinicalTrials.gov (NCT05413122) Evaluating Smoking Cessation Interventions for PWH in South Africa