Details of the Drug Combinations

General Information of This Drug (ID: DMZP7YM)

Drug Name
L-165041   DMZP7YM
Synonyms L165041
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

59 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + L-165041 DCBQ15Y Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aliskiren + L-165041 DCKL8WY Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Allopurinol + L-165041 DCV4RUY Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + L-165041 DCF5WWG BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + L-165041 DCOKBY0 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Docetaxel + L-165041 DC7U00N Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Entacapone + L-165041 DC8VDPL Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + L-165041 DC1Q76F Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + L-165041 DC96ME2 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Mebutamate DCNRHAC Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Picoplatin DC6G8SD Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Gefitinib DCBT09S Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Dantrolene DCZ8TJK Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Kanamycin DC3VPDN Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Triamterene DCYAU4B Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Methotrexate DC26PGU Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Anamorelin DCVUJSJ Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Fomepizole DCKM5VK Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + BHV-0223 DCAP8SE BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Terameprocol DCSEG1N Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Chlorzoxazone DCVK0M0 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Phensuximide DCX6HU1 Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + WAY-100635 DC4S7K5 WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Armodafinil DC7BT4F Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Clopidogrel DCPVU5Q Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Isoproterenol DC12NZQ Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Trifluoperazine DCQSXYI Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Tiagabine DCIV1MQ Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Diazoxide DCNQ277 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Imatinib DC7XL4X Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Probenecid DCC89TS Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Pramipexole DCYKOX6 Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Bortezomib DCV9XKN Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Artemisinin DCN3KXY Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Topotecan DC3L1BI Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Clascoterone DCKKSS0 Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Cefmenoxime DCWR8QU Cefmenoxime Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Maprotiline DCDHQOX Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Leflunomide DCB5S97 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Novobiocin DCHN7VY Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Brincidofovir DCL6JX7 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Quinine DCPY6NZ Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Mycophenolic acid DC16HMO Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Mefloquine DC2ZP2R Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Fosfomycin DC44ZMS Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Lacosamide DC0Q3CA Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Doxorubicin DCDFGE8 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Olmesartan medoxomil DCSB59I Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Auranofin DCAHP24 Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Cerivastatin DC7O5Z0 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Aciclovir DC3F77P Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lacosamide + L-165041 DCDQMMT Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + L-165041 DCTD6E9 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + L-165041 DCNU1DG Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Oxyphenbutazone + L-165041 DCDH93H Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Repaglinide + L-165041 DCA2IMT Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
SCH 727965 + L-165041 DCRF3RC SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triapine + L-165041 DC493L7 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ursodeoxycholic acid + L-165041 DCL1BJ6 Ursodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2691).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.