Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7OHSX)

Drug Name

2-phenylpiperidine hydrochloride Drug Info

Synonyms

2-Phenylpiperidine; 3466-80-6; 2-phenyl-piperidine; Piperidine, 2-phenyl-; 2-phenyl piperidine; EINECS 222-422-6; PubChem8019; (Piperidin-2-yl)benzene; ACMC-1AG1G; AC1L2U2P; AC1Q1H0F; SCHEMBL938781; SCHEMBL11523711; CTK1C4792; MolPort-000-147-784; WGIAUTGOUJDVEI-UHFFFAOYSA-N; KS-00000N7T; ALBB-006245; SBB022661; STK312087; BBL022420; AKOS000184053; AKOS016344001; FS-1688; MCULE-8351203351; ACN-027346; KB-84880; AM803744; SC-48762; TR-014336; ST2404539; AB0089977; ST45091094; P2005; BB 0254270; A6090; FT-0656912; CS-0028391; K-7884; J-019700

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 17814274
CAS Number: CAS 3466-81-7
TTD Drug ID: DM7OHSX

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Dopamine transporter (DAT)	TTVBI8W	SC6A3_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Dopamine transporter (DAT)	DTT	SLC6A3	4	2.609	5.233	3.7

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Dopamine transporter (DAT)	DTT	SLC6A3	1.08E-03	-3.08	-1.99

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate. J Med Chem. 2007 May 31;50(11):2718-31.