Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDBI5S)

Drug Name

Octane-1-sulfonyl fluoride Drug Info

Synonyms

octane-1-sulfonyl fluoride; 1-Octanesulfonyl fluoride; 40630-63-5; octanesulfonyl fluoride; 1-Octanesulphonyl fluoride; UNII-8G6E848M0E; EINECS 255-012-0; CHEMBL499569; 8G6E848M0E; n-octane-sulfonyl fluoride; N-octanesulfonylfluoride; AC1Q4OYH; AC1L4QJC; SCHEMBL678663; DTXSID3028009; CTK4I3469; BDBM50247008; ACM40630635

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 162019
CAS Number: CAS 40630-63-5
TTD Drug ID: DMDBI5S

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cannabinoid receptor 1 (CB1)	TT6OEDT	CNR1_HUMAN	Inhibitor	[1]
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Fatty acid amide hydrolase (FAAH)	DTT	FAAH	5.744	5.044	4.818	5.984
Cannabinoid receptor 1 (CB1)	DTT	CNR1	2.907	4.667	2.982	3.678

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Cannabinoid receptor 1 (CB1)	DTT	CNR1	5.59E-02	-0.22	-0.45
Cannabinoid receptor 1 (CB1)	DTT	CNR1	7.68E-01	-0.06	-0.46

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5875-8.