Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDYZRS)

Drug Name
BPS-804 Drug Info
Synonyms Anti-sclerostin antibody (osteoporosis/hypophophatasia), Novartis
Indication
Disease Entry ICD 11 Status REF
Metabolic bone disease FB8Y Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMDYZRS

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sclerostin (SOST) TTYRO4F SOST_HUMAN Not Available [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Metabolic bone disease
ICD Disease Classification FB8Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Sclerostin (SOST) DTT SOST 1.11E-01 0.9 2.87
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT01806610) Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease. U.S. National Institutes of Health.
2 WO patent application no. 2010,1001,79, Self-forming gel system for sustained drug delivery.