Details of the Drug

General Information of Drug (ID: DMDYZRS)

Drug Name

BPS-804

Synonyms

Anti-sclerostin antibody (osteoporosis/hypophophatasia), Novartis

Indication

Disease Entry	ICD 11	Status	REF
Metabolic bone disease	FB8Y	Phase 2	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Metabolic bone disease

ICD Disease Classification

FB8Y

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Sclerostin (SOST)	DTT	SOST	1.11E-01	0.9	2.87

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT01806610) Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease. U.S. National Institutes of Health.
2	WO patent application no. 2010,1001,79, Self-forming gel system for sustained drug delivery.