Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMH4AGL)

• Drug Name: Tetraethylene Glycol Drug Info
• Synonyms: TETRAETHYLENE GLYCOL; 112-60-7; Tetraglycol; 2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))diethanol; HI-Dry; Carbitol, diethyl; 3,6,9-Trioxaundecane-1,11-diol; Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-; Tetra(ethylene glycol); NSC 1262; 2,2'-[oxybis(ethane-2,1-diyloxy)]diethanol; Bis[2-(2-hydroxyethoxy)ethyl] ether; HSDB 843; Ethanol, 2,2'-(oxybis(ethyleneoxy))di-; 3,6,9-Trioxaundecan-1,11-diol; EINECS 203-989-9; BRN 1634320; PEG-4; AI3-01838; 2,2'-[oxybis(2,1-ethanediyloxy)]diethanol; CHEBI:44920; UWHCKJMYHZGTIT-UHFFFAOYSA-N

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 8200
  ChEBI ID: CHEBI:44920
  CAS Number: CAS 112-60-7
  TTD Drug ID: DMH4AGL

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.