Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMI785L)

Drug Name

3-hydroxy-2-methoxybenzaldehyde Drug Info

Synonyms

3-hydroxy-2-methoxybenzaldehyde; 66495-88-3; CHEMBL507918; 3-hydroxy-2-methoxy-benzaldehyde; hydroxy-methoxy-benzaldehyde; SCHEMBL470709; 2-methoxy-3-hydroxybenzaldehyde; CTK1J4694; DTXSID70473025; GRIWJVSWLJHHEM-UHFFFAOYSA-N; MolPort-002-462-004; Benzaldehyde,3-hydroxy-2-methoxy-; KS-00000B2L; Benzaldehyde, 3-hydroxy-2-methoxy-; ZINC12505037; BDBM50266963; 5891AJ; AKOS000119267; MB03871; SY025931; CS-11591; KB-236283; MFCD06656119 (95%)

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11804953
CAS Number: CAS 66495-88-3
TTD Drug ID: DMI785L

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg Med Chem. 2009 Apr 15;17(8):3207-11.