General Information of Drug (ID: DMI785L)

Drug Name
3-hydroxy-2-methoxybenzaldehyde
Synonyms
3-hydroxy-2-methoxybenzaldehyde; 66495-88-3; CHEMBL507918; 3-hydroxy-2-methoxy-benzaldehyde; hydroxy-methoxy-benzaldehyde; SCHEMBL470709; 2-methoxy-3-hydroxybenzaldehyde; CTK1J4694; DTXSID70473025; GRIWJVSWLJHHEM-UHFFFAOYSA-N; MolPort-002-462-004; Benzaldehyde,3-hydroxy-2-methoxy-; KS-00000B2L; Benzaldehyde, 3-hydroxy-2-methoxy-; ZINC12505037; BDBM50266963; 5891AJ; AKOS000119267; MB03871; SY025931; CS-11591; KB-236283; MFCD06656119 (95%)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 152.15
Logarithm of the Partition Coefficient (xlogp) 1
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C8H8O3
IUPAC Name
3-hydroxy-2-methoxybenzaldehyde
Canonical SMILES
COC1=C(C=CC=C1O)C=O
InChI
InChI=1S/C8H8O3/c1-11-8-6(5-9)3-2-4-7(8)10/h2-5,10H,1H3
InChIKey
GRIWJVSWLJHHEM-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11804953
CAS Number
66495-88-3
TTD ID
D0C9ZY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Carbonic anhydrase II (CA-II) TTANPDJ CAH2_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Carbonic anhydrase II (CA-II) DTT CA2 7.95E-08 0.52 0.33
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg Med Chem. 2009 Apr 15;17(8):3207-11.