Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMIYLXU)

Drug Name

1-(4-ethyl-2,5-dimethoxyphenyl)propan-2-amine Drug Info

Synonyms

2,5-Dimethoxy-4-ethylamphetamine; 1-(4-ethyl-2,5-dimethoxyphenyl)propan-2-amine; 22004-32-6; DOET; CHEMBL8224; NCGC00247691-01; SCHEMBL1740704; DOET,(-); AC1L1D54; CTK4E8216; BDBM81965; HXJKWPGVENNMCC-UHFFFAOYSA-N; 4-Ethyl-2,5-dimethoxyamphetamine; PDSP2_000785; CAS_62066; PDSP1_001371; PDSP2_001355; PDSP1_000797; NSC_62066; DB01467; ACM22004326; 2,5-dimethoxy-4-ethylamphetamine (''DOEt''); L001150; Benzeneethanamine,4-ethyl-2,5-dimethoxy-a-methyl-; 1-(4-Ethyl-2,5-dimethoxyphenyl)-2-propanamine #; Phenethylamine, 4-ethyl-2,5-dimeth

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 27402
CAS Number: CAS 22004-32-6
TTD Drug ID: DMIYLXU

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 2A receptor (HTR2A)	TTJQOD7	5HT2A_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 2A receptor (HTR2A)	DTT	HTR2A	4.84	4.904	4.652	4.129

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 2A receptor (HTR2A)	DTT	HTR2A	1.68E-01	-0.3	-0.14
5-HT 2A receptor (HTR2A)	DTT	HTR2A	5.59E-01	0.15	0.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands. Bioorg Med Chem. 2008 Apr 15;16(8):4661-9.