General Information of Drug (ID: DMQIFJ9)

Drug Name
2-Furan-2-yl-4,5-dihydro-1H-imidazole Drug Info
Synonyms
2-Furan-2-yl-4,5-dihydro-1H-imidazole; 2-(furan-2-yl)-4,5-dihydro-1H-imidazole; 40029-93-4; CHEMBL14410; 2-(2-furyl)-4,5-dihydro-1H-imidazole; AC1LHNFC; BAS 00087895; 2-(2-furyl)imidazoline; 2-(2-imidazolin-2-yl)furan; 2-(1-Imidazoline-2-yl)furan; CTK5J7407; DTXSID40357040; MolPort-001-914-212; HMS1698J05; ZINC4992560; BDBM50138501; 2536AE; AKOS000301450; MCULE-8474767921; ST072486; TR-043590
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
840808
CAS Number
CAS 40029-93-4
TTD Drug ID
DMQIFJ9

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type A (MAO-A) TT3WG5C AOFA_HUMAN Inhibitor [1]
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Monoamine oxidase type B (MAO-B) DTT MAOB 9.367 6.907 8.237 8.409
Monoamine oxidase type A (MAO-A) DTT MAOA 7.207 8.159 9.043 7.711
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type B (MAO-B) DTT MAOB 2.65E-02 1.12E-02 0.07
Monoamine oxidase type A (MAO-A) DTT MAOA 8.14E-01 0.05 0.1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Binding of an imidazopyridoindole at imidazoline I2 receptors. Bioorg Med Chem Lett. 2004 Jan 19;14(2):527-9.