Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMSB8WQ)

Drug Name

6,11-dihydro-5H-benzo[a]carbazole Drug Info

Synonyms

6,11-dihydro-5H-benzo[a]carbazole; 21064-49-3; 5H-Benzo[a]carbazole, 6,11-dihydro-; 1,2,7-trihydrobenzo[a]4aH-carbazole; ST076800; 5,11-Dihydro-6H-benzo[a]carbazole; 5,11-DIHYDRO-6H-BENZO(A)CARBAZOLE; NSC168810; AC1L6RUQ; Maybridge1_006237; AC1Q1H7M; CHEMBL239937; Aza-heterocyclic Derivative, 7; SCHEMBL12126575; HMS559D11; CTK0J8060; BDBM19186; DTXSID40305026; MolPort-000-737-601; ZX-AN022290; ALBB-023776; ZINC1023865; CCG-20433; STK874208; BBL028411; 5,6-Dihydro-11H-benzo[a]carbazole; AKOS000547063; MCULE-4710620349; NSC-168810; RH 00

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 297591
CAS Number: CAS 21064-49-3
TTD Drug ID: DMSB8WQ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type A (MAO-A)	TT3WG5C	AOFA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type A (MAO-A)	DTT	MAOA	7.207	8.159	9.043	7.711

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type A (MAO-A)	DTT	MAOA	8.14E-01	0.05	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives. J Med Chem. 2007 Nov 1;50(22):5364-71.