General Information of Drug (ID: DMSB8WQ)

Drug Name
6,11-dihydro-5H-benzo[a]carbazole
Synonyms
6,11-dihydro-5H-benzo[a]carbazole; 21064-49-3; 5H-Benzo[a]carbazole, 6,11-dihydro-; 1,2,7-trihydrobenzo[a]4aH-carbazole; ST076800; 5,11-Dihydro-6H-benzo[a]carbazole; 5,11-DIHYDRO-6H-BENZO(A)CARBAZOLE; NSC168810; AC1L6RUQ; Maybridge1_006237; AC1Q1H7M; CHEMBL239937; Aza-heterocyclic Derivative, 7; SCHEMBL12126575; HMS559D11; CTK0J8060; BDBM19186; DTXSID40305026; MolPort-000-737-601; ZX-AN022290; ALBB-023776; ZINC1023865; CCG-20433; STK874208; BBL028411; 5,6-Dihydro-11H-benzo[a]carbazole; AKOS000547063; MCULE-4710620349; NSC-168810; RH 00
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 219.28
Logarithm of the Partition Coefficient (xlogp) 4
Rotatable Bond Count (rotbonds) 0
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 0
Chemical Identifiers
Formula
C16H13N
IUPAC Name
6,11-dihydro-5H-benzo[a]carbazole
Canonical SMILES
C1CC2=C(C3=CC=CC=C31)NC4=CC=CC=C24
InChI
InChI=1S/C16H13N/c1-2-6-12-11(5-1)9-10-14-13-7-3-4-8-15(13)17-16(12)14/h1-8,17H,9-10H2
InChIKey
UPUQYBJFFYMNQK-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
297591
CAS Number
21064-49-3
TTD ID
D0E5VT

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type A (MAO-A) TT3WG5C AOFA_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type A (MAO-A) DTT MAOA 8.14E-01 0.05 0.1
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives. J Med Chem. 2007 Nov 1;50(22):5364-71.